| Transcriptional architecture and chromatin landscape of the core circadian clock in mammals N Koike, SH Yoo, HC Huang, V Kumar, C Lee, TK Kim, JS Takahashi science 338 (6105), 349-354, 2012 | 1500 | 2012 |
| Posttranslational mechanisms regulate the mammalian circadian clock C Lee, JP Etchegaray, FRA Cagampang, ASI Loudon, SM Reppert Cell 107 (7), 855-867, 2001 | 1471 | 2001 |
| Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis KM Ramsey, J Yoshino, CS Brace, D Abrassart, Y Kobayashi, B Marcheva, ... Science 324 (5927), 651-654, 2009 | 1301 | 2009 |
| Rhythmic histone acetylation underlies transcription in the mammalian circadian clock JP Etchegaray, C Lee, PA Wade, SM Reppert Nature 421 (6919), 177-182, 2003 | 828 | 2003 |
| Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression SM Siepka, SH Yoo, J Park, W Song, V Kumar, Y Hu, C Lee, ... Cell 129 (5), 1011-1023, 2007 | 625 | 2007 |
| SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins L Busino, F Bassermann, A Maiolica, C Lee, PM Nolan, SIH Godinho, ... science 316 (5826), 900-904, 2007 | 609 | 2007 |
| Circadian homeostasis of liver metabolism suppresses hepatocarcinogenesis NM Kettner, H Voicu, MJ Finegold, C Coarfa, A Sreekumar, N Putluri, ... Cancer cell 30 (6), 909-924, 2016 | 472 | 2016 |
| Targeted Disruption of the mPer3 Gene: Subtle Effects on Circadian Clock Function LP Shearman, X Jin, C Lee, SM Reppert, DR Weaver Molecular and cellular biology 20 (17), 6269-6275, 2000 | 415 | 2000 |
| A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo SH Yoo, CH Ko, PL Lowrey, ED Buhr, E Song, S Chang, OJ Yoo, ... Proceedings of the National Academy of Sciences 102 (7), 2608-2613, 2005 | 387 | 2005 |
| Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex C Lee, V Parikh, T Itsukaichi, K Bae, I Edery Science 271 (5256), 1740-1744, 1996 | 380 | 1996 |
| PER and TIM Inhibit the DNA Binding Activity of a Drosophila CLOCK-CYC/dBMAL1 Heterodimer without Disrupting Formation of the Heterodimer: a Basis for … C Lee, K Bae, I Edery Molecular and cellular biology 19 (8), 5316-5325, 1999 | 343 | 1999 |
| The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER–TIM complex C Lee, K Bae, I Edery Neuron 21 (4), 857-867, 1998 | 306 | 1998 |
| Circadian Regulation of a Drosophila Homolog of the Mammalian Clock Gene: PER and TIM Function as Positive Regulators K Bae, C Lee, D Sidote, K Chuang, I Edery Molecular and cellular biology 18 (10), 6142-6151, 1998 | 300 | 1998 |
| Circadian dysfunction induces leptin resistance in mice NM Kettner, SA Mayo, J Hua, C Lee, DD Moore, L Fu Cell metabolism 22 (3), 448-459, 2015 | 272 | 2015 |
| Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism R Chen, A Schirmer, Y Lee, H Lee, V Kumar, SH Yoo, JS Takahashi, ... Molecular cell 36 (3), 417-430, 2009 | 270 | 2009 |
| Essential roles of CKIδ and CKIε in the mammalian circadian clock H Lee, R Chen, Y Lee, S Yoo, C Lee Proceedings of the National Academy of Sciences 106 (50), 21359-21364, 2009 | 232 | 2009 |
| The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1 H Lee, R Chen, H Kim, JP Etchegaray, DR Weaver, C Lee Proceedings of the National Academy of Sciences 108 (39), 16451-16456, 2011 | 214 | 2011 |
| mTOR signaling regulates central and peripheral circadian clock function C Ramanathan, ND Kathale, D Liu, C Lee, DA Freeman, JB Hogenesch, ... PLoS genetics 14 (5), e1007369, 2018 | 197 | 2018 |
| Direct association between mouse PERIOD and CKIε is critical for a functioning circadian clock C Lee, DR Weaver, SM Reppert Molecular and cellular biology, 2004 | 192 | 2004 |
| Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis MP Antoch, VY Gorbacheva, O Vykhovanets, IA Toshkov, RV Kondratov, ... Cell Cycle 7 (9), 1197-1204, 2008 | 190 | 2008 |
