Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function CJ Kelly, L Zheng, EL Campbell, B Saeedi, CC Scholz, AJ Bayless, ... Cell host & microbe 17 (5), 662-671, 2015 | 1522 | 2015 |
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia U Bruning, L Cerone, Z Neufeld, SF Fitzpatrick, A Cheong, CC Scholz, ... Molecular and cellular biology 31 (19), 4087-4096, 2011 | 350 | 2011 |
Frequently asked questions in hypoxia research RH Wenger, V Kurtcuoglu, CC Scholz, HH Marti, D Hoogewijs Hypoxia, 35-43, 2015 | 256 | 2015 |
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function MM Tambuwala, EP Cummins, CR Lenihan, J Kiss, M Stauch, CC Scholz, ... Gastroenterology 139 (6), 2093-2101, 2010 | 231 | 2010 |
The effect of HIF on metabolism and immunity CT Taylor, CC Scholz Nature Reviews Nephrology 18 (9), 573-587, 2022 | 219 | 2022 |
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia SF Fitzpatrick, MM Tambuwala, U Bruning, B Schaible, CC Scholz, ... The Journal of Immunology 186 (2), 1091-1096, 2011 | 203 | 2011 |
Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways CC Scholz, MAS Cavadas, MM Tambuwala, E Hams, J Rodríguez, ... Proceedings of the National Academy of Sciences 110 (46), 18490-18495, 2013 | 200 | 2013 |
Targeting the HIF pathway in inflammation and immunity CC Scholz, CT Taylor Current opinion in pharmacology 13 (4), 646-653, 2013 | 179 | 2013 |
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network LK Nguyen, MAS Cavadas, CC Scholz, SF Fitzpatrick, U Bruning, ... Journal of cell science 126 (6), 1454-1463, 2013 | 141 | 2013 |
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells EP Cummins, KM Oliver, CR Lenihan, SF Fitzpatrick, U Bruning, ... The Journal of Immunology 185 (7), 4439-4445, 2010 | 125 | 2010 |
FIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1 CC Scholz, J Rodriguez, C Pickel, S Burr, J Fabrizio, KA Nolan, ... PLoS biology 14 (1), e1002347, 2016 | 100 | 2016 |
REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia MAS Cavadas, M Mesnieres, B Crifo, MC Manresa, AC Selfridge, ... Scientific reports 5 (1), 17851, 2015 | 79 | 2015 |
Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia TA Agbor, A Cheong, KM Comerford, CC Scholz, U Bruning, A Clarke, ... Journal of Biological Chemistry 286 (6), 4718-4726, 2011 | 79 | 2011 |
REST is a hypoxia-responsive transcriptional repressor MAS Cavadas, M Mesnieres, B Crifo, MC Manresa, AC Selfridge, ... Scientific Reports 6 (1), 31355, 2016 | 72 | 2016 |
Hypercapnia suppresses the HIF-dependent adaptive response to hypoxia AC Selfridge, MAS Cavadas, CC Scholz, EL Campbell, LC Welch, ... Journal of Biological Chemistry 291 (22), 11800-11808, 2016 | 69 | 2016 |
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype F Imeri, KA Nolan, AM Bapst, S Santambrogio, I Abreu-Rodríguez, ... Kidney international 95 (2), 375-387, 2019 | 52 | 2019 |
Hydroxylase-dependent regulation of the NF-κB pathway CC Scholz, CT Taylor Biological chemistry 394 (4), 479-493, 2013 | 52 | 2013 |
Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells K Gutsche, EB Randi, V Blank, D Fink, RH Wenger, C Leo, CC Scholz Free Radical Biology and Medicine 101, 129-142, 2016 | 50 | 2016 |
Hypoxic Regulation of NF‐κB Signaling EP Cummins, KM Comerford, C Scholz, U Bruning, CT Taylor Methods in enzymology 435, 479-492, 2007 | 40 | 2007 |
Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation CE Keogh, CC Scholz, J Rodriguez, AC Selfridge, A von Kriegsheim, ... Journal of Biological Chemistry 292 (27), 11561-11571, 2017 | 39 | 2017 |