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Traver Hart
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High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
15932015
A census of human soluble protein complexes
PC Havugimana, GT Hart, T Nepusz, H Yang, AL Turinsky, Z Li, PI Wang, ...
Cell 150 (5), 1068-1081, 2012
9412012
The shieldin complex mediates 53BP1-dependent DNA repair
SM Noordermeer, S Adam, D Setiaputra, M Barazas, SJ Pettitt, AK Ling, ...
Nature 560 (7716), 117-121, 2018
5432018
How complete are current yeast and human protein-interaction networks?
GT Hart, AK Ramani, EM Marcotte
Genome biology 7, 1-9, 2006
5332006
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens
T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ...
G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017
4722017
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
T Hart, KR Brown, F Sircoulomb, R Rottapel, J Moffat
Mol Syst Biol 10, 733, 2014
3712014
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis
X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ...
Nature cell biology 25 (3), 404-414, 2023
3582023
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ...
Nature 559 (7713), 285-289, 2018
3432018
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60-68, 2017
3102017
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
GT Hart, I Lee, EM Marcotte
BMC bioinformatics 8, 1-11, 2007
2922007
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ...
Nature 586 (7827), 120-126, 2020
2822020
Finding the active genes in deep RNA-seq gene expression studies
T Hart, HK Komori, S LaMere, K Podshivalova, DR Salomon
BMC genomics 14, 1-7, 2013
2572013
BAGEL: a computational framework for identifying essential genes from pooled library screens
T Hart, J Moffat
BMC bioinformatics 17, 1-7, 2016
2472016
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells
G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ...
Cell reports 27 (3), 971-986. e9, 2019
1962019
HumanNet v2: human gene networks for disease research
S Hwang, CY Kim, S Yang, E Kim, T Hart, EM Marcotte, I Lee
Nucleic acids research 47 (D1), D573-D580, 2019
1922019
Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells
CM Toledo, Y Ding, P Hoellerbauer, RJ Davis, R Basom, EJ Girard, E Lee, ...
Cell reports 13 (11), 2425-2439, 2015
1772015
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ...
Nature communications 11 (1), 3701, 2020
1572020
Identifying chemogenetic interactions from CRISPR screens with drugZ
M Colic, G Wang, M Zimmermann, K Mascall, M McLaughlin, L Bertolet, ...
Genome medicine 11 (1), 1-12, 2019
1502019
Natural variation in gene expression modulates the severity of mutant phenotypes
V Vu, AJ Verster, M Schertzberg, T Chuluunbaatar, M Spensley, D Pajkic, ...
Cell 162 (2), 391-402, 2015
1502015
MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes
YA Grigoryev, SM Kurian, T Hart, AA Nakorchevsky, C Chen, D Campbell, ...
The Journal of Immunology 187 (5), 2233-2243, 2011
1272011
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Articles 1–20