Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the … Z Eshhar, T Waks, G Gross, DG Schindler Proceedings of the National Academy of Sciences 90 (2), 720-724, 1993 | 1818 | 1993 |
A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli. et al. Capel MS, Engelman DM, Freeborn BR, Kjeldgaard M, Langer JA ... Science 238 (4832), 1403-06, 1987 | 340 | 1987 |
Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain. P Hwu, GE Shafer, J Treisman, DG Schindler, G Gross, R Cowherd, ... Journal of Experimental Medicine 178 (1), 361-366, 1993 | 300 | 1993 |
Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors. I Stancovski, DG Schindler, T Waks, Y Yarden, M Sela, Z Eshhar The Journal of Immunology 151 (11), 6577-6582, 1993 | 266 | 1993 |
Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. SD González A, Jiménez A, Vázquez D, Davies JE Biochim Biophys Acta 521 (2), 459-69, 1978 | 243* | 1978 |
Chimeric receptor genes and cells transformed therewith Z Eshhar, D Schindler, T Waks, G Gross US Patent 7,741,465, 2010 | 240 | 2010 |
Functional expression of chimeric receptor genes in human T cells Z Eshhar, T Waks, A Bendavid, DG Schindler Journal of immunological methods 248 (1-2), 67-76, 2001 | 231 | 2001 |
Specific cleavage of ribosomal RNA caused by alpha sarcin DJE Schindler DG Nucleic Acids Res 4 (4), 1097-1110, 1977 | 203 | 1977 |
Chimeric receptor genes and cells transformed therewith Z Eshhar, D Schindler, T Waks, G Gross, SA Rosenberg, P Hwu US Patent 8,211,422, 2012 | 173 | 2012 |
Chimeric receptor genes and cells transformed therewith ZA Eshhar, D Schindler, T Waks, G Gross, SA Rosenberg, P Hwu US Patent App. 08/547,263, 2002 | 173* | 2002 |
Fc-dependent expression of CD137 on human NK cells: insights into “agonistic” effects of anti-CD137 monoclonal antibodies W Lin, CJ Voskens, X Zhang, DG Schindler, A Wood, E Burch, Y Wei, ... Blood 112 (3), 699-707, 2008 | 161 | 2008 |
Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region H Voliovitch, DG Schindler, YR Hadari, SI Taylor, D Accili, Y Zick Journal of Biological Chemistry 270 (30), 18083-18087, 1995 | 142 | 1995 |
Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation D Friedmann-Morvinski, A Bendavid, T Waks, D Schindler, Z Eshhar Blood 105 (8), 3087-3093, 2005 | 118 | 2005 |
Location of sites in human lipocortin I that are phosphorylated by protein tyrosine kinases and protein kinases A and C L Varticovski, SB Chahwala, M Whitman, L Cantley, D Schindler, ... Biochemistry 27 (10), 3682-3690, 1988 | 117 | 1988 |
Structural convergence in the active sites of a family of catalytic antibodies JB Charbonnier, B Golinelli-Pimpaneau, B Gigant, DS Tawfik, R Chap, ... Science 275 (5303), 1140-1142, 1997 | 112 | 1997 |
Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes JH Pinthus, T Waks, K Kaufman-Francis, DG Schindler, A Harmelin, ... Cancer Research 63 (10), 2470-2476, 2003 | 110 | 2003 |
The T-body approach: potential for cancer immunotherapy Z Eshhar, N Bach, CJ Fitzer-Attas, G Grosse, J Lustgarten, T Waks, ... Springer seminars in immunopathology 18 (2), 199-209, 1996 | 105 | 1996 |
Trichodermin resistance--mutation affecting eukaryotic ribosomes. DJ Schindler D, Grant P Nature 248 (448), 535-6, 1974 | 92 | 1974 |
Harnessing Syk family tyrosine kinases as signaling domains for chimeric single chain of the variable domain receptors: optimal design for T cell activation CJ Fitzer-Attas, DG Schindler, T Waks, Z Eshhar The Journal of Immunology 160 (1), 145-154, 1998 | 88 | 1998 |
Mapping of trichodermin resistance in Saccharomyces cerevisiae: a genetic locus for a component of the 60S ribsomal subunit PG Grant, D Schindler, JE Davies Genetics 83 (4), 667-673, 1976 | 86 | 1976 |