Seth B. Coffelt, Ph.D.
Seth B. Coffelt, Ph.D.
University of Glasgow/CRUK Beatson Institute
Verified email at - Homepage
Cited by
Cited by
The role of myeloid cells in the promotion of tumour angiogenesis
C Murdoch, M Muthana, SB Coffelt, CE Lewis
Nature reviews cancer 8 (8), 618-631, 2008
IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
SB Coffelt, K Kersten, CW Doornebal, J Weiden, K Vrijland, CS Hau, ...
Nature 522 (7556), 345-348, 2015
Neutrophils in cancer: neutral no more
SB Coffelt, MD Wellenstein, KE de Visser
Nature Reviews Cancer 16 (7), 431-446, 2016
Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses
SL Tomchuck, KJ Zwezdaryk, SB Coffelt, RS Waterman, ES Danka, ...
Stem cells 26 (1), 99-107, 2008
Tumor-associated macrophages: effectors of angiogenesis and tumor progression
SB Coffelt, R Hughes, CE Lewis
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1796 (1), 11-18, 2009
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
MD Wellenstein, SB Coffelt, DEM Duits, MH van Miltenburg, M Slagter, ...
Nature 572 (7770), 538-542, 2019
Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions
SB Coffelt, AO Tal, A Scholz, M De Palma, S Patel, C Urbich, SK Biswas, ...
Cancer research 70 (13), 5270-5280, 2010
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells
SB Coffelt, FC Marini, K Watson, KJ Zwezdaryk, JL Dembinski, ...
Proceedings of the National Academy of Sciences 106 (10), 3806-3811, 2009
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
HY Fang, R Hughes, C Murdoch, SB Coffelt, SK Biswas, AL Harris, ...
Blood, The Journal of the American Society of Hematology 114 (4), 844-859, 2009
γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer
B Silva-Santos, S Mensurado, SB Coffelt
Nature Reviews Cancer 19 (7), 392-404, 2019
The autophagic paradox in cancer therapy
WKK Wu, SB Coffelt, CH Cho, XJ Wang, CW Lee, FKL Chan, J Yu, ...
Oncogene 31 (8), 939-953, 2012
TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice
AF Welford, D Biziato, SB Coffelt, S Nucera, M Fisher, F Pucci, C Di Serio, ...
The Journal of clinical investigation 121 (5), 1969-1973, 2011
Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion
SB Coffelt, YY Chen, M Muthana, AF Welford, AO Tal, A Scholz, KH Plate, ...
The Journal of Immunology 186 (7), 4183-4190, 2011
Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors
SB Coffelt, CE Lewis, L Naldini, JM Brown, N Ferrara, M De Palma
The American journal of pathology 176 (4), 1564-1576, 2010
Emerging roles of the host defense peptide LL‐37 in human cancer and its potential therapeutic applications
WKK Wu, G Wang, SB Coffelt, AM Betancourt, CW Lee, D Fan, K Wu, J Yu, ...
International Journal of Cancer 127 (8), 1741-1747, 2010
Ovarian cancers overexpress the antimicrobial protein hCAP‐18 and its derivative LL‐37 increases ovarian cancer cell proliferation and invasion
SB Coffelt, RS Waterman, L Florez, KH Bentrup, KJ Zwezdaryk, ...
International journal of cancer 122 (5), 1030-1039, 2008
Immune-mediated mechanisms influencing the efficacy of anticancer therapies
SB Coffelt, KE de Visser
Trends in immunology 36 (4), 198-216, 2015
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
C Salvagno, M Ciampricotti, S Tuit, CS Hau, A van Weverwijk, SB Coffelt, ...
Nature cell biology 21 (4), 511-521, 2019
Use of macrophages to target therapeutic adenovirus to human prostate tumors
M Muthana, A Giannoudis, SD Scott, HY Fang, SB Coffelt, FJ Morrow, ...
Cancer research 71 (5), 1805-1815, 2011
Inflammation lights the way to metastasis
SB Coffelt, KE De Visser
Nature 507 (7490), 48-49, 2014
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