| Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet AM Leconte, GT Hwang, S Matsuda, P Capek, Y Hari, FE Romesberg Journal of the American Chemical Society 130 (7), 2336-2343, 2008 | 203 | 2008 |
| Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution BC Dickinson, AM Leconte, B Allen, KM Esvelt, DR Liu Proceedings of the National Academy of Sciences 110 (22), 9007-9012, 2013 | 141 | 2013 |
| Discovery and biological characterization of geranylated RNA in bacteria CE Dumelin, Y Chen, AM Leconte, YG Chen, DR Liu Nature chemical biology 8 (11), 913-919, 2012 | 138 | 2012 |
| Minor groove hydrogen bonds and the replication of unnatural base pairs S Matsuda, AM Leconte, FE Romesberg Journal of the American Chemical Society 129 (17), 5551-5557, 2007 | 88 | 2007 |
| Polymerase evolution: efforts toward expansion of the genetic code AM Leconte, L Chen, FE Romesberg Journal of the American Chemical Society 127 (36), 12470-12471, 2005 | 84 | 2005 |
| Efforts towards expansion of the genetic alphabet: pyridone and methyl pyridone nucleobases AM Leconte, S Matsuda, GT Hwang, FE Romesberg Angewandte Chemie-International Edition 45 (26), 4326-4329, 2006 | 70 | 2006 |
| Stability and polymerase recognition of pyridine nucleobase analogues: Role of minor‐groove H‐bond acceptors Y Kim, AM Leconte, Y Hari, FE Romesberg Angewandte Chemie 118 (46), 7973-7976, 2006 | 65 | 2006 |
| A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes AM Leconte, BC Dickinson, DD Yang, IA Chen, B Allen, DR Liu Biochemistry 52 (8), 1490-1499, 2013 | 60 | 2013 |
| Directed evolution of DNA polymerases for next generation sequencing AM Leconte, MP Patel, LE Sass, P McInerney, M Jarosz, L Kung, ... Angewandte Chemie (International ed. in English) 49 (34), 5921, 2010 | 46 | 2010 |
| An efficiently extended class of unnatural base pairs AM Leconte, S Matsuda, FE Romesberg Journal of the American Chemical Society 128 (21), 6780-6781, 2006 | 41 | 2006 |
| Taq DNA polymerase mutants and 2′-modified sugar recognition HJ Schultz, AM Gochi, HE Chia, AL Ogonowsky, S Chiang, N Filipovic, ... Biochemistry 54 (38), 5999-6008, 2015 | 31 | 2015 |
| Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication Y Hari, GT Hwang, AM Leconte, N Joubert, M Hocek, FE Romesberg ChemBioChem 9 (17), 2796-2799, 2008 | 29 | 2008 |
| Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase MH Duyzend, CT Clark, SL Simmons, WB Johnson, AM Larson, ... Journal of Enzyme Inhibition and Medicinal Chemistry 27 (6), 784-794, 2012 | 15 | 2012 |
| Polymerase recognition and stability of fluoro‐substituted pyridone nucleobase analogues GT Hwang, AM Leconte, FE Romesberg ChemBioChem 8 (13), 1606-1611, 2007 | 15 | 2007 |
| Statistical coupling analysis-guided library design for the discovery of mutant luciferases MD Liu, EA Warner, CE Morrissey, CW Fick, TS Wu, MY Ornelas, ... Biochemistry 57 (5), 663-671, 2018 | 14 | 2018 |
| A broader take on DNA AM Leconte, FE Romesberg Nature 444 (7119), 553-555, 2006 | 11 | 2006 |
| Amplify this! DNA and RNA get a third base pair AM Leconte, FE Romesberg Nature Methods 3 (9), 667-668, 2006 | 9 | 2006 |
| Design and discovery of new combinations of mutant DNA polymerases and modified DNA substrates SL Rosenblum, AG Weiden, EL Lewis, AL Ogonowsky, HE Chia, ... ChemBioChem 18 (8), 816-823, 2017 | 7 | 2017 |
| Engineering nucleobases and polymerases for an expanded genetic alphabet AM Leconte, FE Romesberg Protein engineering, 291-313, 2009 | 3 | 2009 |
| Biochemical Analysis Leads to Improved Orthogonal Bioluminescent Tools SJ Williams, JA Gewing‐Mullins, WK Lieberman, B Kolbaba‐Kartchner, ... ChemBioChem 24 (6), e202200726, 2023 | 2 | 2023 |
