Vicki L. McGovern, PhD
Vicki L. McGovern, PhD
Dirección de correo verificada de osu.edu
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Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
KD Foust, X Wang, VL McGovern, L Braun, AK Bevan, AM Haidet, TT Le, ...
Nature biotechnology 28 (3), 271-274, 2010
6482010
A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse
PN Porensky, C Mitrpant, VL McGovern, AK Bevan, KD Foust, BK Kaspar, ...
Human molecular genetics 21 (7), 1625-1638, 2012
2512012
Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect
TO Gavrilina, VL McGovern, E Workman, TO Crawford, RG Gogliotti, ...
Human molecular genetics 17 (8), 1063-1075, 2008
2092008
Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery
AK Bevan, KR Hutchinson, KD Foust, L Braun, VL McGovern, ...
Human molecular genetics 19 (20), 3895-3905, 2010
2002010
Embryonic motor axon development in the severe SMA mouse
VL McGovern, TO Gavrilina, CE Beattie, AHM Burghes
Human molecular genetics 17 (18), 2900-2909, 2008
1692008
Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose–response study in mice and nonhuman primates
K Meyer, L Ferraiuolo, L Schmelzer, L Braun, V McGovern, S Likhite, ...
Molecular Therapy 23 (3), 477-487, 2015
1662015
Temporal requirement for high SMN expression in SMA mice
TT Le, VL McGovern, IE Alwine, X Wang, A Massoni-Laporte, MM Rich, ...
Human molecular genetics 20 (18), 3578-3591, 2011
1202011
Natural history of infantile‐onset spinal muscular atrophy
SJ Kolb, CS Coffey, JW Yankey, K Krosschell, WD Arnold, SB Rutkove, ...
Annals of neurology 82 (6), 883-891, 2017
1062017
A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy
M Ruggiu, VL McGovern, F Lotti, L Saieva, DK Li, S Kariya, UR Monani, ...
Molecular and cellular biology 32 (1), 126-138, 2012
992012
Baseline results of the Neuro NEXT spinal muscular atrophy infant biomarker study
SJ Kolb, CS Coffey, JW Yankey, K Krosschell, WD Arnold, SB Rutkove, ...
Annals of clinical and translational neurology 3 (2), 132-145, 2016
632016
SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA
VL McGovern, CC Iyer, WD Arnold, SE Gombash, PG Zaworski, ...
Human molecular genetics 24 (19), 5524-5541, 2015
442015
Electrophysiological biomarkers in spinal muscular atrophy: proof of concept
W David Arnold, PN Porensky, VL McGovern, CC Iyer, S Duque, X Li, ...
Annals of clinical and translational neurology 1 (1), 34-44, 2014
442014
Antisense oligonucleotides and spinal muscular atrophy: skipping along
AHM Burghes, VL McGovern
Genes & development 24 (15), 1574-1579, 2010
442010
Plastin 3 expression does not modify spinal muscular atrophy severity in the∆ 7 SMA mouse
VL McGovern, A Massoni-Laporte, X Wang, TT Le, HT Le, CE Beattie, ...
PloS one 10 (7), e0132364, 2015
362015
SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice
SE Gombash, CJ Cowley, JA Fitzgerald, CC Iyer, D Fried, VL McGovern, ...
Human molecular genetics 24 (13), 3847-3860, 2015
342015
VACM-1 receptor is specifically expressed in rabbit vascular endothelium and renal collecting tubule
M Burnatowska-Hledin, IB Lazdins, L Listenberger, P Zhao, ...
American Journal of Physiology-Renal Physiology 276 (2), F199-F209, 1999
341999
Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA
CC Iyer, VL McGovern, JD Murray, SE Gombash, PG Zaworski, KD Foust, ...
Human molecular genetics 24 (21), 6160-6173, 2015
312015
The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy
W Arnold, VL McGovern, B Sanchez, J Li, KM Corlett, SJ Kolb, ...
Neurobiology of disease 87, 116-123, 2016
302016
A targeted gain of function screen in the embryonic CNS of Drosophila
VL McGovern, CA Pacak, ST Sewell, ML Turski, MA Seeger
Mechanisms of development 120 (10), 1193-1207, 2003
292003
Complete sequencing of the SMN2 gene in SMA patients detects SMN gene deletion junctions and variants in SMN2 that modify the SMA phenotype
C Ruhno, VL McGovern, MR Avenarius, PJ Snyder, TW Prior, FC Nery, ...
Human genetics 138 (3), 241-256, 2019
142019
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20