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Léo Aubert
Léo Aubert
Dirección de correo verificada de uclouvain.be
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EPCR expression marks UM171-expanded CD34+ cord blood stem cells
I Fares, J Chagraoui, B Lehnertz, T MacRae, N Mayotte, E Tomellini, ...
Blood, The Journal of the American Society of Hematology 129 (25), 3344-3351, 2017
1892017
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ...
Nature communications 11 (1), 3701, 2020
1482020
The receptor tyrosine kinase AXL is required at multiple steps of the metastatic cascade during HER2-positive breast cancer progression
MA Goyette, S Duhamel, L Aubert, A Pelletier, P Savage, MP Thibault, ...
Cell reports 23 (5), 1476-1490, 2018
1412018
Inhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsules
AL Lainé, A Clavreul, A Rousseau, C Tétaud, A Vessieres, E Garcion, ...
Nanomedicine: Nanotechnology, Biology and Medicine 10 (8), 1667-1677, 2014
422014
NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib
L Aubert, M Guilbert, C Corbet, E Génot, E Adriaenssens, T Chassat, ...
Oncotarget 6 (12), 9807, 2015
372015
Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities
S Cardin, M Bilodeau, M Roussy, L Aubert, T Milan, L Jouan, A Rouette, ...
Blood advances 3 (21), 3307-3321, 2019
302019
ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2
R Lévêque, C Corbet, L Aubert, M Guilbert, C Lagadec, E Adriaenssens, ...
Cancer Letters 449, 196-206, 2019
282019
NF45 and NF90 regulate mitotic gene expression by competing with Staufen-mediated mRNA decay
S Nourreddine, G Lavoie, J Paradis, KB El Kadhi, A Meant, L Aubert, ...
Cell Reports 31 (7), 2020
222020
Extracellular signal-regulated kinases 1 and 2 phosphorylate Gab2 to promote a negative-feedback loop that attenuates phosphoinositide 3-kinase/Akt signaling
X Zhang, G Lavoie, A Méant, L Aubert, M Cargnello, A Haman, T Hoang, ...
Molecular and Cellular Biology 37 (7), e00357-16, 2017
212017
Proteomic analysis reveals a role for RSK in p120-catenin phosphorylation and melanoma cell-cell adhesion
A Méant, B Gao, G Lavoie, S Nourreddine, F Jung, L Aubert, ...
Molecular & Cellular Proteomics 19 (1), 50-64, 2020
192020
Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
S Trouvilliez, J Cicero, R Lévêque, L Aubert, C Corbet, A Van Outryve, ...
Journal of experimental & clinical cancer research 41 (1), 110, 2022
122022
The receptor tyrosine kinase AXL is required at multiple steps of the metastatic Cascade during HER2-positive breast Cancer progression. Cell Rep. 2018; 23: 1476–90
MA Goyette, S Duhamel, L Aubert, A Pelletier, P Savage, MP Thibault, ...
Epub 2018/05/03. doi: 10.1016/j. celrep. 2018.04. 019. PubMed PMID: 29719259, 0
12
Targeting copper metabolism to defeat KRAS-driven colorectal cancer
L Aubert, N Nandagopal, PP Roux
Molecular & Cellular Oncology 7 (6), 1822123, 2020
52020
CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216
V Gress, M Roussy, L Boulianne, M Bilodeau, S Cardin, N El-Hachem, ...
Blood Advances, bloodadvances. 2022008899, 2023
22023
Coordination of Pro-and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion
J Chagraoui, E Tomellini, L Aubert, I Fares, JF Spinella, S Girard, ...
Blood 132, 2555, 2018
22018
Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors
L Aubert, E Bastien, O Renoult, C Guilbaud, K Özkan, D Brusa, C Bouzin, ...
EMBO reports, 1-21, 2024
12024
Combined use of a trka inhibitor and an epha2 inhibitor for using in the treatment of solid cancers, and method for the prognosis of survival of a patient who has a solid cancer
R Toillon, X Le Bourhis, C Corbet, L Aubert, M Guilbert
US Patent App. 15/511,739, 2017
12017
Tumor acidosis-induced DNA damage response and tetraploidy: implications for ATM and ATR inhibitors.
L Aubert, E Bastien, O Renoult, C Guilbaud, K Özkan, D Brusa, C Bouzin, ...
EMBO Reports, 2024
2024
Deciphering the interplay between circadian clock and tumor metabolism to optimize anticancer chronotherapies
L Aubert, K Özkan, C Guilbaud, P Bruno, S Srhir, O Feron
BACR (Belgian Association for Cancer Research) Annual Meeting, 2023
2023
Deciphering the interplay between circadian rhythms and metabolic preferences in colorectal cancer cells and 3D spheroids.
L Aubert, K Özkan, S Srhir, P Bruno, C Guilbaud, O Feron
Gordon Research Conference" Clocks Across the Phylogenetic Tree, from Single …, 2023
2023
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