Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy GP Gao, MR Alvira, L Wang, R Calcedo, J Johnston, JM Wilson Proceedings of the National Academy of Sciences 99 (18), 11854-11859, 2002 | 1633 | 2002 |
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer SE Raper, N Chirmule, FS Lee, NA Wivel, A Bagg, G Gao, JM Wilson, ... Molecular genetics and metabolism 80 (1-2), 148-158, 2003 | 1558 | 2003 |
Clades of Adeno-associated viruses are widely disseminated in human tissues G Gao, LH Vandenberghe, MR Alvira, Y Lu, R Calcedo, X Zhou, ... Journal of virology 78 (12), 6381-6388, 2004 | 999 | 2004 |
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. KJ Fisher, GP Gao, MD Weitzman, R DeMatteo, JF Burda, JM Wilson Journal of virology 70 (1), 520-532, 1996 | 697 | 1996 |
Gene therapy vectors based on adeno-associated virus type 1 W Xiao, N Chirmule, SC Berta, B McCullough, G Gao, JM Wilson Journal of virology 73 (5), 3994-4003, 1999 | 644 | 1999 |
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 578 | 2016 |
Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses R Calcedo, LH Vandenberghe, G Gao, J Lin, JM Wilson The Journal of infectious diseases 199 (3), 381-390, 2009 | 552 | 2009 |
New recombinant serotypes of AAV vectors G Gao, LH Vandenberghe, JM Wilson Current gene therapy 5 (3), 285-297, 2005 | 517 | 2005 |
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. G Gao, Y Yang, JM Wilson Journal of virology 70 (12), 8934-8943, 1996 | 438 | 1996 |
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages Y Zhang, N Chirmule, G Gao, R Qian, M Croyle, B Joshi, J Tazelaar, ... Molecular Therapy 3 (5), 697-707, 2001 | 429 | 2001 |
A Pilot Study of In Vivo Liver-Directed Gene Transfer with an Adenoviral Vector in Partial Ornithine Transcarbamylase Deficiency SE Raper, M Yudkoff, N Chirmule, GP Gao, F Nunes, ZJ Haskal, EE Furth, ... Human gene therapy 13 (1), 163-175, 2002 | 413 | 2002 |
Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column A Auricchio, M Hildinger, E O'Connor, GP Gao, JM Wilson Human gene therapy 12 (1), 71-76, 2001 | 392 | 2001 |
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors MA Schnell, Y Zhang, J Tazelaar, G Gao, QC Yu, R Qian, SJ Chen, ... Molecular Therapy 3 (5), 708-722, 2001 | 387 | 2001 |
Adeno-associated viruses undergo substantial evolution in primates during natural infections G Gao, MR Alvira, S Somanathan, Y Lu, LH Vandenberghe, JJ Rux, ... Proceedings of the National Academy of Sciences 100 (10), 6081-6086, 2003 | 364 | 2003 |
Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver N Tao, GP Gao, M Parr, J Johnston, T Baradet, JM Wilson, J Barsoum, ... Molecular Therapy 3 (1), 28-35, 2001 | 356 | 2001 |
Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer X Ye, VM Rivera, P Zoltick, F Cerasoli, MA Schnell, G Gao, JV Hughes, ... Science 283 (5398), 88-91, 1999 | 353 | 1999 |
Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer VM Rivera, G Gao, RL Grant, MA Schnell, PW Zoltick, LW Rozamus, ... Blood 105 (4), 1424-1430, 2005 | 309 | 2005 |
Replication-defective vector based on a chimpanzee adenovirus SF Farina, G Gao, ZQ Xiang, JJ Rux, RM Burnett, MR Alvira, J Marsh, ... Journal of virology 75 (23), 11603-11613, 2001 | 298 | 2001 |
Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat LT Bish, K Morine, MM Sleeper, J Sanmiguel, D Wu, G Gao, JM Wilson, ... Human gene therapy 19 (12), 1359-1368, 2008 | 295 | 2008 |
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina J Bennett, AM Maguire, AV Cideciyan, M Schnell, E Glover, V Anand, ... Proceedings of the National Academy of Sciences 96 (17), 9920-9925, 1999 | 286 | 1999 |