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Alexander Yakunin
Alexander Yakunin
University of Toronto (Canada), Bangor University (UK)
Verified email at bangor.ac.uk
Title
Cited by
Cited by
Year
Evolution and classification of the CRISPR–Cas systems
KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ...
Nature Reviews Microbiology 9 (6), 467-477, 2011
34952011
An updated evolutionary classification of CRISPR–Cas systems
KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ...
Nature reviews microbiology 13 (11), 722-736, 2015
30302015
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ...
Nature Reviews Microbiology 18 (2), 67-83, 2020
21052020
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family
E Kuznetsova, M Proudfoot, CF Gonzalez, G Brown, MV Omelchenko, ...
Journal of Biological Chemistry 281 (47), 36149-36161, 2006
3712006
A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair
M Babu, N Beloglazova, R Flick, C Graham, T Skarina, B Nocek, ...
Molecular microbiology 79 (2), 484-502, 2011
3612011
In situ proteolysis for protein crystallization and structure determination
A Dong, X Xu, AM Edwards
Nature methods 4 (12), 1019-1021, 2007
2942007
Heavy metal removal by bioaccumulation using genetically engineered microorganisms
P Diep, R Mahadevan, AF Yakunin
Frontiers in bioengineering and biotechnology 6, 157, 2018
2882018
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats
N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ...
Journal of Biological Chemistry 283 (29), 20361-20371, 2008
2722008
Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction
N Beloglazova, R Flick, A Tchigvintsev, G Brown, A Popovic, B Nocek, ...
Journal of Biological Chemistry 288 (12), 8101-8110, 2013
2662013
Enzyme genomics: Application of general enzymatic screens to discover new enzymes
E Kuznetsova, M Proudfoot, SA Sanders, J Reinking, A Savchenko, ...
FEMS microbiology reviews 29 (2), 263-279, 2005
1932005
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
N Beloglazova, P Petit, R Flick, G Brown, A Savchenko, AF Yakunin
The EMBO journal 30 (22), 4616-4627, 2011
1722011
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
C Schneider, T Oellerich, HM Baldauf, SM Schwarz, D Thomas, R Flick, ...
Nature medicine 23 (2), 250-255, 2017
1702017
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases
A Tchigvintsev, X Xu, A Singer, C Chang, G Brown, M Proudfoot, H Cui, ...
Journal of molecular biology 402 (3), 524-538, 2010
1672010
Molecular basis of formaldehyde detoxification: characterization of two S-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG
CF Gonzalez, M Proudfoot, G Brown, Y Korniyenko, H Mori, ...
Journal of Biological Chemistry 281 (20), 14514-14522, 2006
1582006
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria
B Nocek, S Kochinyan, M Proudfoot, G Brown, E Evdokimova, J Osipiuk, ...
Proceedings of the National Academy of Sciences 105 (46), 17730-17735, 2008
1562008
Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica
M Kube, TN Chernikova, Y Al-Ramahi, A Beloqui, N Lopez-Cortez, ...
Nature communications 4 (1), 2156, 2013
1542013
Biochemical and structural insights into enzymatic depolymerization of polylactic acid and other polyesters by microbial carboxylesterases
M Hajighasemi, BP Nocek, A Tchigvintsev, G Brown, R Flick, X Xu, H Cui, ...
Biomacromolecules 17 (6), 2027-2039, 2016
1522016
Riboneogenesis in yeast
MF Clasquin, E Melamud, A Singer, JR Gooding, X Xu, A Dong, H Cui, ...
Cell 145 (6), 969-980, 2011
1482011
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli
R Sanishvili, AF Yakunin, RA Laskowski, T Skarina, E Evdokimova, ...
Journal of Biological Chemistry 278 (28), 26039-26045, 2003
1452003
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis
G Brown, A Singer, M Proudfoot, T Skarina, Y Kim, C Chang, ...
Biochemistry 47 (21), 5724-5735, 2008
1332008
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