| Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2278 | 2016 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1865* | 2020 |
| HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ... Nature medicine 23 (4), 517-525, 2017 | 1003 | 2017 |
| A compendium of mutational signatures of environmental agents JE Kucab, X Zou, S Morganella, M Joel, AS Nanda, E Nagy, C Gomez, ... Cell 177 (4), 821-836. e16, 2019 | 559 | 2019 |
| The topography of mutational processes in breast cancer genomes S Morganella, LB Alexandrov, D Glodzik, X Zou, H Davies, J Staaf, ... Nature communications 7 (1), 11383, 2016 | 286 | 2016 |
| Computational investigation of DNA detection using graphene nanopores C Sathe, X Zou, JP Leburton, K Schulten ACS nano 5 (11), 8842-8851, 2011 | 224 | 2011 |
| A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies A Degasperi, TD Amarante, J Czarnecki, S Shooter, X Zou, D Glodzik, ... Nature cancer 1 (2), 249-263, 2020 | 208 | 2020 |
| Mutational signatures: emerging concepts, caveats and clinical applications G Koh, A Degasperi, X Zou, S Momen, S Nik-Zainal Nature Reviews Cancer 21 (10), 619-637, 2021 | 201 | 2021 |
| Detection and quantification of methylation in DNA using solid-state nanopores J Shim, GI Humphreys, BM Venkatesan, JM Munz, X Zou, C Sathe, ... Scientific reports 3 (1), 1389, 2013 | 201 | 2013 |
| Cytosine methylation alters DNA mechanical properties PMD Severin, X Zou, HE Gaub, K Schulten Nucleic acids research 39 (20), 8740-8751, 2011 | 181 | 2011 |
| Substitution mutational signatures in whole-genome–sequenced cancers in the UK population A Degasperi, X Zou, T Dias Amarante, A Martinez-Martinez, GCC Koh, ... Science 376 (6591), abl9283, 2022 | 175 | 2022 |
| Validating the concept of mutational signatures with isogenic cell models X Zou, M Owusu, R Harris, SP Jackson, JI Loizou, S Nik-Zainal Nature communications 9 (1), 1744, 2018 | 162 | 2018 |
| Recognition of methylated DNA through methyl-CpG binding domain proteins X Zou, W Ma, IA Solov'Yov, C Chipot, K Schulten Nucleic acids research 40 (6), 2747-2758, 2012 | 145 | 2012 |
| A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage X Zou, GCC Koh, AS Nanda, A Degasperi, K Urgo, TI Roumeliotis, ... Nature cancer 2 (6), 643-657, 2021 | 120 | 2021 |
| Whole-genome sequencing reveals breast cancers with mismatch repair deficiency H Davies, S Morganella, CA Purdie, SJ Jang, E Borgen, H Russnes, ... Cancer research 77 (18), 4755-4762, 2017 | 111 | 2017 |
| A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers D Glodzik, S Morganella, H Davies, PT Simpson, Y Li, X Zou, ... Nature genetics 49 (3), 341-348, 2017 | 92 | 2017 |
| Nanoelectromechanics of methylated DNA in a synthetic nanopore U Mirsaidov, W Timp, X Zou, V Dimitrov, K Schulten, AP Feinberg, G Timp Biophysical journal 96 (4), L32-L34, 2009 | 77 | 2009 |
| Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells FJ Rouhani, X Zou, P Danecek, C Badja, TD Amarante, G Koh, Q Wu, ... Nature Genetics 54 (9), 1406-1416, 2022 | 63 | 2022 |
| Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation AB Brinkman, S Nik-Zainal, F Simmer, FG Rodríguez-González, M Smid, ... Nature communications 10 (1), 1749, 2019 | 63 | 2019 |
| Effects of cytosine hydroxymethylation on DNA strand separation PMD Severin, X Zou, K Schulten, HE Gaub Biophysical journal 104 (1), 208-215, 2013 | 50 | 2013 |
