Follow
Christopher Winrow
Christopher Winrow
Cyclerion Therapeutics
Verified email at cyclerion.com
Title
Cited by
Cited by
Year
Distribution of histone deacetylases 1–11 in the rat brain
RS Broide, JM Redwine, N Aftahi, W Young, FE Bloom, CJ Winrow
Journal of Molecular Neuroscience 31, 47-58, 2007
4302007
Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl …
CD Cox, MJ Breslin, DB Whitman, JD Schreier, GB McGaughey, ...
Journal of medicinal chemistry 53 (14), 5320-5332, 2010
4212010
Orexin receptors: pharmacology and therapeutic opportunities
TE Scammell, CJ Winrow
Annual review of pharmacology and toxicology 51 (1), 243-266, 2011
4152011
Promotion of sleep by suvorexant—a novel dual orexin receptor antagonist
CJ Winrow, AL Gotter, CD Cox, SM Doran, PL Tannenbaum, MJ Breslin, ...
Journal of neurogenetics 25 (1-2), 52-61, 2011
2982011
The concise guide to PHARMACOLOGY 2015/16: Overview
SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ...
British journal of pharmacology 172 (24), 5729-5743, 2015
2442015
Adult mouse brain gene expression patterns bear an embryologic imprint
MA Zapala, I Hovatta, JA Ellison, L Wodicka, JA Del Rio, R Tennant, ...
Proceedings of the National Academy of Sciences 102 (29), 10357-10362, 2005
2102005
Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity
CJ Winrow, ML Hemming, DM Allen, GB Quistad, JE Casida, C Barlow
Nature genetics 33 (4), 477-485, 2003
2102003
Ataxia telangiectasia mutated is essential during adult neurogenesis
DM Allen, H van Praag, J Ray, Z Weaver, CJ Winrow, TA Carter, ...
Genes & development 15 (5), 554-566, 2001
1992001
International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology
AL Gotter, AL Webber, PJ Coleman, JJ Renger, CJ Winrow
Pharmacological reviews 64 (3), 389-420, 2012
1932012
Discovery and development of orexin receptor antagonists as therapeutics for insomnia
CJ Winrow, JJ Renger
British journal of pharmacology 171 (2), 283-293, 2014
1682014
Pharmacological characterization of MK-6096–a dual orexin receptor antagonist for insomnia
CJ Winrow, AL Gotter, CD Cox, PL Tannenbaum, SL Garson, SM Doran, ...
Neuropharmacology 62 (2), 978-987, 2012
1602012
Evidence that mouse brain neuropathy target esterase is a lysophospholipase
GB Quistad, C Barlow, CJ Winrow, SE Sparks, JE Casida
Proceedings of the National Academy of Sciences 100 (13), 7983-7987, 2003
1572003
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ...
Nature Structural & Molecular Biology 23 (4), 293-299, 2016
1562016
Discovery of [(2R,5R)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin …
PJ Coleman, JD Schreier, CD Cox, MJ Breslin, DB Whitman, MJ Bogusky, ...
ChemMedChem 7 (3), 415-424, 2012
1382012
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure
CJ Winrow, KQ Tanis, DR Reiss, AM Rigby, JM Uslaner, VN Uebele, ...
Neuropharmacology 58 (1), 185-194, 2010
1302010
The discovery of suvorexant, the first orexin receptor drug for insomnia
PJ Coleman, AL Gotter, WJ Herring, CJ Winrow, JJ Renger
Annual review of pharmacology and toxicology 57 (1), 509-533, 2017
1252017
Orexin receptors as therapeutic drug targets
AL Gotter, AJ Roecker, R Hargreaves, PJ Coleman, CJ Winrow, ...
Progress in brain research 198, 163-188, 2012
1232012
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition
JM Uslaner, SJ Tye, DM Eddins, X Wang, SV Fox, AT Savitz, J Binns, ...
Science translational medicine 5 (179), 179ra44-179ra44, 2013
1112013
Evidence for orexinergic mechanisms in migraine
J Hoffmann, W Supronsinchai, S Akerman, AP Andreou, CJ Winrow, ...
Neurobiology of disease 74, 137-143, 2015
1022015
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold
AL Gotter, CJ Winrow, J Brunner, SL Garson, SV Fox, J Binns, CM Harrell, ...
BMC neuroscience 14, 1-16, 2013
972013
The system can't perform the operation now. Try again later.
Articles 1–20