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James Pearce Hall
James Pearce Hall
Associate Professor in Biomolecular Structure and Education, University of Reading
Dirección de correo verificada de reading.ac.uk
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Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes
H Niyazi, JP Hall, K O'sullivan, G Winter, T Sorensen, JM Kelly, CJ Cardin
Nature Chemistry 4 (8), 621-628, 2012
2132012
Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
JP Hall, K O’Sullivan, A Naseer, JA Smith, JM Kelly, CJ Cardin
Proceedings of the National Academy of Sciences 108 (43), 17610-17614, 2011
1362011
The importance of loop length on the stability of i-motif structures
SP Gurung, C Schwarz, JP Hall, CJ Cardin, JA Brazier
Chemical communications 51 (26), 5630-5632, 2015
1152015
X-ray Crystal Structure of rac-[Ru(phen)2dppz]2+ with d(ATGCAT)2 Shows Enantiomer Orientations and Water Ordering
JP Hall, D Cook, SR Morte, P McIntyre, K Buchner, H Beer, DJ Cardin, ...
Journal of the American Chemical Society 135 (34), 12652-12659, 2013
942013
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
JP Hall, FE Poynton, PM Keane, SP Gurung, JA Brazier, DJ Cardin, ...
Nature Chemistry 7 (12), 961-967, 2015
692015
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru (phen) 2 (dppz)] 2+ light-switch compound in solution and when …
FE Poynton, JP Hall, PM Keane, C Schwarz, IV Sazanovich, M Towrie, ...
Chemical Science 7 (5), 3075-3084, 2016
642016
Structural Studies Reveal Enantiospecific Recognition of a DNA G‐Quadruplex by a Ruthenium Polypyridyl Complex
K McQuaid, H Abell, SP Gurung, DR Allan, G Winter, T Sorensen, ...
Angewandte Chemie International Edition 58 (29), 9881-9885, 2019
432019
Delta chirality ruthenium ‘light-switch’complexes can bind in the minor groove of DNA with five different binding modes
JP Hall, PM Keane, H Beer, K Buchner, G Winter, TL Sorensen, DJ Cardin, ...
Nucleic Acids Research 44 (19), 9472-9482, 2016
422016
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium (II) Dipyridophenazine Complex
PM Keane, FE Poynton, JP Hall, IV Sazanovich, M Towrie, ...
Angewandte Chemie International Edition 54 (29), 8364-8368, 2015
402015
Enantiomeric conformation controls rate and yield of photoinduced electron transfer in DNA sensitized by Ru (II) Dipyridophenazine complexes
PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ...
The Journal of Physical Chemistry Letters 6 (4), 734-738, 2015
312015
Ruthenium polypyridyl complex bound to a unimolecular chair-form G-quadruplex
KT McQuaid, S Takahashi, L Baumgaertner, DJ Cardin, NG Paterson, ...
Journal of the American Chemical Society 144 (13), 5956-5964, 2022
272022
The structural effect of methyl substitution on the binding of polypyridyl Ru–dppz complexes to DNA
JP Hall, H Beer, K Buchner, DJ Cardin, CJ Cardin
Organometallics 34 (11), 2481-2486, 2015
272015
Controlled dehydration of a ruthenium complex–DNA crystal induces reversible DNA kinking
JP Hall, J Sanchez-Weatherby, C Alberti, CH Quimper, K O’Sullivan, ...
Journal of the American Chemical Society 136 (50), 17505-17512, 2014
272014
Three's a crowd–stabilisation, structure, and applications of DNA triplexes
M Dalla Pozza, A Abdullrahman, CJ Cardin, G Gasser, JP Hall
Chemical Science 13 (35), 10193-10215, 2022
232022
Guanine can direct binding specificity of Ru–dipyridophenazine (Dppz) complexes to DNA through steric effects
JP Hall, SP Gurung, J Henle, P Poidl, J Andersson, P Lincoln, G Winter, ...
Chemistry–A European Journal 23 (21), 4981-4985, 2017
212017
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuII Complex due to Structural Change in the Minor Groove
PM Keane, JP Hall, FE Poynton, BC Poulsen, SP Gurung, IP Clark, ...
Chemistry–A European Journal 23 (43), 10344-10351, 2017
192017
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides
YR Baker, C Thorpe, J Chen, LM Poller, L Cox, P Kumar, WF Lim, L Lie, ...
Nature communications 13 (1), 4036, 2022
172022
X‐ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru‐dppz Complexes
K McQuaid, JP Hall, JA Brazier, DJ Cardin, CJ Cardin
Chemistry–A European Journal 24 (59), 15859-15867, 2018
172018
Three thymine/adenine binding modes of the ruthenium complex Λ-[Ru (TAP) 2 (dppz)] 2+ to the G-quadruplex forming sequence d (TAGGGTT) shown by X-ray crystallography
K McQuaid, JP Hall, L Baumgaertner, DJ Cardin, CJ Cardin
Chemical communications 55 (62), 9116-9119, 2019
162019
Monitoring guanine photo-oxidation by enantiomerically resolved Ru (II) dipyridophenazine complexes using inosine-substituted oligonucleotides
PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ...
Faraday Discussions 185, 455-469, 2015
152015
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