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Jay Prakash Jain
Jay Prakash Jain
Sr. Investigator I, Novartis
Dirección de correo verificada de novartis.com
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Spiroindolone KAE609 for falciparum and vivax malaria
NJ White, S Pukrittayakamee, AP Phyo, R Rueangweerayut, F Nosten, ...
New England Journal of Medicine 371 (5), 403-410, 2014
2702014
Role of polyanhydrides as localized drug carriers
JP Jain, S Modi, AJ Domb, N Kumar
Journal of Controlled Release 103 (3), 541-563, 2005
2342005
Functionalized polymersomes for biomedical applications
PV Pawar, SV Gohil, JP Jain, N Kumar
Polymer Chemistry 4 (11), 3160-3176, 2013
1372013
Self assembling polymers as polymersomes for drug delivery
J Prakash Jain, W Yenet Ayen, N Kumar
Current pharmaceutical design 17 (1), 65-79, 2011
902011
Fatty acid based biodegradable polymer
JP Jain, M Sokolsky, N Kumar, AJ Domb
Polymer Reviews 48 (1), 156-191, 2008
892008
Exploiting EPR in polymer drug conjugate delivery for tumor targeting
S Modi, J Prakash Jain, AJ Domb, N Kumar
Current pharmaceutical design 12 (36), 4785-4796, 2006
842006
Polyanhydrides as localized drug delivery carrier: an update
JP Jain, D Chitkara, N Kumar
Expert opinion on drug delivery 5 (8), 889-907, 2008
832008
Development of amphotericin B loaded polymersomes based on (PEG) 3-PLA co-polymers: Factors affecting size and in vitro evaluation
JP Jain, N Kumar
European journal of pharmaceutical sciences 40 (5), 456-465, 2010
802010
Self Assembly of Amphiphilic (PEG)3-PLA Copolymer as Polymersomes: Preparation, Characterization, and Their Evaluation As Drug Carrier
JP Jain, N Kumar
Biomacromolecules 11 (4), 1027-1035, 2010
762010
A first-in-human randomized, double-blind, placebo-controlled, single-and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess …
FJ Leong, R Li, JP Jain, G Lefèvre, B Magnusson, TT Diagana, P Pertel
Antimicrobial agents and chemotherapy 58 (10), 6209-6214, 2014
742014
Hydroxy fatty acid based polyanhydride as drug delivery system: Synthesis, characterization, in vitro degradation, drug release, and biocompatibility
JP Jain, S Modi, N Kumar
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2008
562008
Biodegradable polymers in drug delivery
JP Jain, W Yenet Ayen, AJ Domb, N Kumar
Biodegradable polymers in clinical use and clinical development, 1-58, 2011
482011
Simultaneous determination of hydrazinocurcumin and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation
R Rathore, JP Jain, A Srivastava, SM Jachak, N Kumar
Journal of pharmaceutical and biomedical analysis 46 (2), 374-380, 2008
442008
Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria
TT Hien, NJ White, NT Thuy-Nhien, NT Hoa, PD Thuan, J Tarning, ...
Antimicrobial agents and chemotherapy 61 (2), 10.1128/aac. 01940-16, 2017
382017
Bioavailability of lumefantrine is significantly enhanced with a novel formulation approach, an outcome from a randomized, open-label pharmacokinetic study in healthy volunteers
JP Jain, FJ Leong, L Chen, S Kalluri, V Koradia, DS Stein, MC Wolf, ...
Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00868-17, 2017
352017
Amphotericin-B-Loaded Polymersomes Formulation (PAMBO) Based on (PEG)3-PLA Copolymers: An in Vivo Evaluation in a Murine Model
JP Jain, M Jatana, A Chakrabarti, N Kumar
Molecular pharmaceutics 8 (1), 204-212, 2011
352011
Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility
S Modi, JP Jain, AJ Domb, N Kumar
European journal of pharmaceutics and biopharmaceutics 64 (3), 277-286, 2006
352006
KAE609 (cipargamin), a new spiroindolone agent for the treatment of malaria: evaluation of the absorption, distribution, metabolism, and excretion of a single oral 300-mg dose …
SEW Huskey, C Zhu, A Fredenhagen, J Kühnöl, A Luneau, Z Jian, Z Yang, ...
Drug Metabolism and disposition 44 (5), 672-682, 2016
332016
Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609 (cipargamin) and piperaquine
DS Stein, JP Jain, M Kangas, G Lefèvre, S Machineni, P Griffin, J Lickliter
Antimicrobial agents and chemotherapy 59 (6), 3493-3500, 2015
292015
Effect of PEG chain length and hydrophilic weight fraction on polymersomes prepared from branched (PEG)3‐PLA co‐polymers
WY Ayen, B Chintankumar, JP Jain, N Kumar
Polymers for Advanced Technologies 22 (1), 158-165, 2011
282011
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Artículos 1–20