| Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 435 | 2019 |
| Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation P Srivastava, H Yang, K Ellis-Guardiola, JC Lewis Nature communications 6 (1), 7789, 2015 | 189 | 2015 |
| Evolving artificial metalloenzymes via random mutagenesis H Yang, AM Swartz, HJ Park, P Srivastava, K Ellis-Guardiola, DM Upp, ... Nature chemistry 10 (3), 318-324, 2018 | 121 | 2018 |
| A general method for artificial metalloenzyme formation through strain‐promoted azide–alkyne cycloaddition H Yang, P Srivastava, C Zhang, JC Lewis ChemBioChem 15 (2), 223-227, 2014 | 114 | 2014 |
| Engineered ribosyl-1-kinase enables concise synthesis of molnupiravir, an antiviral for COVID-19 JA McIntosh, T Benkovics, SM Silverman, MA Huffman, J Kong, ... ACS Central Science 7 (12), 1980-1985, 2021 | 100 | 2021 |
| Pyridyl‐Substituted Corrole Isomers: Synthesis and their Regulation to G‐quadruplex Structures H Ma, M Zhang, D Zhang, R Huang, Y Zhao, H Yang, Y Liu, X Weng, ... Chemistry–An Asian Journal 5 (1), 114-122, 2010 | 39 | 2010 |
| Synthesis of islatravir enabled by a catalytic, enantioselective alkynylation of a ketone NR Patel, CC Nawrat, M McLaughlin, Y Xu, MA Huffman, H Yang, H Li, ... Organic Letters 22 (12), 4659-4664, 2020 | 23 | 2020 |
| A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins A Fryszkowska, C An, O Alvizo, G Banerjee, KA Canada, Y Cao, ... Science 376 (6599), 1321-1327, 2022 | 21 | 2022 |
| Evolving to an ideal synthesis of molnupiravir, an investigational treatment for COVID-19 T Benkovics, J McIntosh, S Silverman, J Kong, P Maligres, T Itoh, H Yang, ... | 21 | 2020 |
| Synthesis and catalytic activity of amino acids and metallopeptides with catalytically active metallocyclic side chains Z Zhang, H Yang, C Zhang, JC Lewis Organometallics 31 (21), 7328-7331, 2012 | 18 | 2012 |
| Synthesis of Isotopically Labeled Anti-HIV Nucleoside Islatravir through a One-Pot Biocatalytic Cascade Reaction S Ren, MA Huffman, AM Whittaker, H Yang, CC Nawrat, DJ Waterhouse, ... Organic Process Research & Development 25 (3), 516-521, 2020 | 4 | 2020 |
| Engineered deoxyribose-phosphate aldolases D Duan, O Alvizo, J Nazor, HC Maniar, JN Riggins, J Vroom, ... US Patent App. 16/460,118, 2020 | 4 | 2020 |
| Synthesis of antiviral nucleosides T Benkovics, PS Fier, A Fryszkowska, MA Huffman, T Itoh, J Kong, ... US Patent App. 18/256,058, 2024 | | 2024 |
| ENGINEERED DEOXYRIBOSE-PHOSPHATE ALDOLASES D Duan, O Alvizo, J Nazor, HC Maniar, JN Riggins, J Vroom, ... US Patent App. 18/503,542, 2024 | | 2024 |
| S-METHYLTHIORIBOSE KINASE POLYPEPTIDES AND PROCESSES FOR MAKING AND USING S-METHYLTHIORIBOSE KINASE POLYPEPTIDES T Benkovics, H Ho, J Mcintosh, GS Murphy, W Pan, D Verma, H Yang US Patent App. 18/256,061, 2024 | | 2024 |
| Engineered deoxyribose-phosphate aldolases D Duan, O Alvizo, J Nazor, HC Maniar, JN Riggins, J Vroom, ... US Patent 11,845,968, 2023 | | 2023 |
| Design of an in vitro biocatalytic cascade for the manufacture of islatravir (vol 366, pg 1255, 2019) A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, PN Devine, ... Science 368 (6488), 2020 | | 2020 |
| Engineering artificial metalloenzyme for selective catalysis H Yang The University of Chicago, 2016 | | 2016 |
| Pyrococcus furiosus prolyl oligopeptidase: A versatile and robust scaffold for the development of artificial metalloenzymes K Ellis-Guardiola, P Srivastava, H Yang ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
| Engineering proteins for selective catalysis H Yang, C Zhang, P Srivastava, K Ellis-Guardiola, J Lewis ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |
Jared C. LewisIndiana UniversityDirección de correo verificada de iu.edu
