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Marcela V Maus
Marcela V Maus
Harvard Medical School
Dirección de correo verificada de mgh.harvard.edu
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ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells
DW Lee, BD Santomasso, FL Locke, A Ghobadi, CJ Turtle, JN Brudno, ...
Biology of blood and marrow transplantation 25 (4), 625-638, 2019
21002019
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...
Science translational medicine 9 (399), eaaa0984, 2017
14702017
Anti-BCMA CAR T-cell therapy bb2121 in relapsed or refractory multiple myeloma
N Raje, J Berdeja, YI Lin, D Siegel, S Jagannath, D Madduri, M Liedtke, ...
New England Journal of Medicine 380 (18), 1726-1737, 2019
13952019
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
GP Linette, EA Stadtmauer, MV Maus, AP Rapoport, BL Levine, L Emery, ...
Blood, The Journal of the American Society of Hematology 122 (6), 863-871, 2013
12032013
Antibody-modified T cells: CARs take the front seat for hematologic malignancies
MV Maus, SA Grupp, DL Porter, CH June
Blood, The Journal of the American Society of Hematology 123 (17), 2625-2635, 2014
10452014
Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce antitumor activity in solid malignancies
GL Beatty, AR Haas, MV Maus, DA Torigian, MC Soulen, G Plesa, ...
Cancer immunology research 2 (2), 112-120, 2014
9022014
CD8+ T-cell responses to adeno-associated virus capsid in humans
F Mingozzi, MV Maus, DJ Hui, DE Sabatino, SL Murphy, JEJ Rasko, ...
Nature medicine 13 (4), 419-422, 2007
8042007
T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
MV Maus, AR Haas, GL Beatty, SM Albelda, BL Levine, X Liu, Y Zhao, ...
Cancer immunology research 1 (1), 26-31, 2013
6522013
Chimeric antigen receptor T cells against CD19 for multiple myeloma
AL Garfall, MV Maus, WT Hwang, SF Lacey, YD Mahnke, JJ Melenhorst, ...
New England Journal of Medicine 373 (11), 1040-1047, 2015
6322015
Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB
MV Maus, AK Thomas, DGB Leonard, D Allman, K Addya, K Schlienger, ...
Nature biotechnology 20 (2), 143-148, 2002
6142002
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...
Nature biotechnology 37 (3), 276-282, 2019
5172019
Recent advances and discoveries in the mechanisms and functions of CAR T cells
RC Larson, MV Maus
Nature Reviews Cancer 21 (3), 145-161, 2021
5142021
Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
L Tang, Y Zheng, MB Melo, L Mabardi, AP Castaño, YQ Xie, N Li, ...
Nature biotechnology 36 (8), 707-716, 2018
4992018
Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma
LA Johnson, J Scholler, T Ohkuri, A Kosaka, PR Patel, SE McGettigan, ...
Science translational medicine 7 (275), 275ra22-275ra22, 2015
4882015
Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
JA Fraietta, KA Beckwith, PR Patel, M Ruella, Z Zheng, DM Barrett, ...
Blood, The Journal of the American Society of Hematology 127 (9), 1117-1127, 2016
4812016
Dominant-negative TGF-β receptor enhances PSMA-targeted human CAR T cell proliferation and augments prostate cancer eradication
CC Kloss, J Lee, A Zhang, F Chen, JJ Melenhorst, SF Lacey, MV Maus, ...
Molecular therapy 26 (7), 1855-1866, 2018
4792018
Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig–coated artificial antigen-presenting cells
M Oelke, MV Maus, D Didiano, CH June, A Mackensen, JP Schneck
Nature medicine 9 (5), 619-625, 2003
4032003
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
BD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ...
Nature biotechnology 37 (9), 1049-1058, 2019
3992019
Engineering and design of chimeric antigen receptors
S Guedan, H Calderon, AD Posey, MV Maus
Molecular Therapy-Methods & Clinical Development 12, 145-156, 2019
3902019
Ibrutinib treatment improves T cell number and function in CLL patients
M Long, K Beckwith, P Do, BL Mundy, A Gordon, AM Lehman, ...
The Journal of clinical investigation 127 (8), 3052-3064, 2017
3402017
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