Jon M Laurent
Jon M Laurent
NYU Langone Health
Verified email at
Cited by
Cited by
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
AH Kachroo, JM Laurent, CM Yellman, AG Meyer, CO Wilke, EM Marcotte
Science 348 (6237), 921-925, 2015
Protein abundances are more conserved than mRNA abundances across diverse taxa
JM Laurent, C Vogel, T Kwon, SA Craig, DR Boutz, HK Huse, K Nozue, ...
Proteomics 10 (23), 4209-4212, 2010
Efforts to make and apply humanized yeast
JM Laurent, JH Young, AH Kachroo, EM Marcotte
Briefings in functional genomics 15 (2), 155-163, 2016
Single-step precision genome editing in yeast using CRISPR-Cas9
A Akhmetov, JM Laurent, J Gollihar, EC Gardner, RK Garge, AD Ellington, ...
Bio-protocol 8 (6), e2765-e2765, 2018
Prediction of gene-phenotype associations in humans, mice, and plants using phenologs
JO Woods, UM Singh-Blom, JM Laurent, KL McGary, EM Marcotte
BMC bioinformatics 14, 1-17, 2013
Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte
PLoS biology 18 (5), e3000627, 2020
A versatile platform for locus-scale genome rewriting and verification
R Brosh, JM Laurent, R Ordoņez, E Huang, MS Hogan, AM Hitchcock, ...
Proceedings of the National Academy of Sciences 118 (10), e2023952118, 2021
Systematic bacterialization of yeast genes identifies a near-universally swappable pathway
AH Kachroo, JM Laurent, A Akhmetov, M Szilagyi-Jones, CD McWhite, ...
Elife 6, e25093, 2017
The many nuanced evolutionary consequences of duplicated genes
AI Teufel, MM Johnson, JM Laurent, AH Kachroo, EM Marcotte, CO Wilke
Molecular biology and evolution 36 (2), 304-314, 2019
Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes
RK Garge, JM Laurent, AH Kachroo, EM Marcotte
Genetics 215 (4), 1153-1169, 2020
Assessment of potential SARS-CoV-2 virus integration into human genome reveals no significant impact on RT-qPCR COVID-19 testing
E Briggs, W Ward, S Rey, D Law, K Nelson, M Bois, N Ostrov, HH Lee, ...
Proceedings of the National Academy of Sciences 118 (44), e2113065118, 2021
Big DNA as a tool to dissect an age-related macular degeneration-associated haplotype
JM Laurent, X Fu, S German, MT Maurano, K Zhang, JD Boeke
Precision Clinical Medicine 2 (1), 1-7, 2019
CREEPY: CRISPR-mediated editing of synthetic episomes in yeast
Y Zhao, C Coelho, S Lauer, M Majewski, JM Laurent, R Brosh, JD Boeke
Nucleic acids research 51 (13), e72-e72, 2023
Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast
M Abdullah, BM Greco, JM Laurent, RK Garge, DR Boutz, M Vandeloo, ...
Cell Reports Methods 3 (5), 2023
Probing the dark matter of the human genome with big DNA
JM Laurent, S Pinglay, L Mitchell, R Brosh
The Biochemist 41 (3), 46-48, 2019
Development and scaling of a sequencing pipeline for genomic surveillance of SARS-CoV-2 in New York City
MJ Hammerling, SC Kang, W Ward, IF Escapa, P Bugga, C Del Castillo, ...
medRxiv, 2022.05. 25.22273991, 2022
Methods and compositions for rapid and high throughput diagnosis
JD Boeke, J Laurent, A Martin, M Paolo
US Patent 11,667,962, 2023
EUAdb: A resource for COVID-19 test development and comparison
A Woronik, HW Shaffer, K Kiontke, JM Laurent, R Zambrano, M Daley, ...
PloS one 16 (8), e0255417, 2021
Big-in: a versatile platform for locus-scale genome rewriting and verification
R Brosh, J Laurent, M Maurano, JD Boeke
US Patent App. 18/248,453, 2023
Molecular neighborhood detection by oligonucleotides
E Marcotte, J Swaminathan, A Ellington, A Boulgakov, J Laurent, R Shroff, ...
US Patent App. 17/146,165, 2021
The system can't perform the operation now. Try again later.
Articles 1–20