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Sieger Leenstra
Sieger Leenstra
hoogleraar neurochirurgie Rotterdam
Dirección de correo verificada de erasmusmc.nl
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Recent advances in the molecular understanding of glioblastoma
FE Bleeker, RJ Molenaar, S Leenstra
Journal of neuro-oncology 108, 11-27, 2012
5622012
IDH1 mutations at residue p.R132 (IDH1R132) occur frequently in high‐grade gliomas but not in other solid tumors
FE Bleeker, S Lamba, S Leenstra, D Troost, T Hulsebos, WP Vandertop, ...
Human mutation 30 (1), 7-11, 2009
4852009
Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins
E Aronica, JA Gorter, H Ijlst‐Keizers, AJ Rozemuller, B Yankaya, ...
European Journal of Neuroscience 17 (10), 2106-2118, 2003
3412003
Neurobehavioral status and health-related quality of life in newly diagnosed high-grade glioma patients
M Klein, MJB . Taphoorn, JJ Heimans, HM van der Ploeg, WP Vandertop, ...
Journal of clinical oncology 19 (20), 4037-4047, 2001
3342001
Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: focal cortical dysplasia and glioneuronal tumors
E Aronica, JA Gorter, GH Jansen, CWM Van Veelen, PC Van Rijen, ...
Neuroscience 118 (2), 417-429, 2003
2782003
The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids
PC De Witt Hamer, AAG Van Tilborg, PP Eijk, P Sminia, D Troost, ...
Oncogene 27 (14), 2091-2096, 2008
2482008
The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone
RJ Molenaar, D Verbaan, S Lamba, C Zanon, JWM Jeuken, ...
Neuro-oncology 16 (9), 1263-1273, 2014
2442014
AKT1E17K in human solid tumours
FE Bleeker, L Felicioni, F Buttitta, S Lamba, L Cardone, M Rodolfo, ...
Oncogene 27 (42), 5648-5650, 2008
2402008
Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain
E Aronica, JA Gorter, S Redeker, EA Van Vliet, M Ramkema, GL Scheffer, ...
Epilepsia 46 (6), 849-857, 2005
2282005
Glioneuronal tumors and medically intractable epilepsy: a clinical study with long-term follow-up of seizure outcome after surgery
E Aronica, S Leenstra, CWM van Veelen, PC van Rijen, TJ Hulsebos, ...
Epilepsy research 43 (3), 179-191, 2001
2082001
Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma
A Balakrishnan, FE Bleeker, S Lamba, M Rodolfo, M Daniotti, A Scarpa, ...
Cancer research 67 (8), 3545-3550, 2007
1972007
Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex
E Aronica, JA Gorter, GH Jansen, S Leenstra, B Yankaya, D Troost
Acta neuropathologica 101, 449-459, 2001
1952001
Functional magnetic resonance imaging for neurosurgical planning in neurooncology
EJ Vlieger, CB Majoie, S Leenstra, GJ Den Heeten
European radiology 14, 1143-1153, 2004
1882004
Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy
E Aronica, B Yankaya, GH Jansen, S Leenstra, CWM Van Veelen, ...
Neuropathology and applied neurobiology 27 (3), 223-237, 2001
1762001
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
LBC Bralten, NK Kloosterhof, R Balvers, A Sacchetti, L Lapre, M Lamfers, ...
Annals of neurology 69 (3), 455-463, 2011
1682011
Expression and distribution of id helix‐loop‐helix proteins in human astrocytic tumors
DAA Vandeputte, D Troost, S Leenstra, H Ijlst‐Keizers, M Ramkema, ...
Glia 38 (4), 329-338, 2002
1632002
Differential effect of surgery and radiotherapy on neurocognitive functioning and health-related quality of life in WHO grade I meningioma patients
D van Nieuwenhuizen, M Klein, LJA Stalpers, S Leenstra, JJ Heimans, ...
Journal of neuro-oncology 84, 271-278, 2007
1402007
Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide
KA Van Nifterik, J Van Den Berg, WF Van Der Meide, N Ameziane, ...
British journal of cancer 103 (1), 29-35, 2010
1282010
Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing
J De Vrij, SLN Maas, M Van Nispen, M Sena-Esteves, RWA Limpens, ...
Nanomedicine 8 (9), 1443-1458, 2013
1242013
Late neurocognitive sequelae in patients with WHO grade I meningioma
M Dijkstra, D van Nieuwenhuizen, LJA Stalpers, M Wumkes, ...
Journal of Neurology, Neurosurgery & Psychiatry 80 (8), 910-915, 2009
1222009
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