| The MLL1-H3K4me3 axis-mediated PD-L1 expression and pancreatic cancer immune evasion C Lu, AV Paschall, H Shi, N Savage, JL Waller, ME Sabbatini, ... JNCI: journal of the National Cancer Institute 109 (6), djw283, 2017 | 221 | 2017 |
| The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells C Lu, PS Redd, JR Lee, N Savage, K Liu Oncoimmunology 5 (12), e1247135, 2016 | 221 | 2016 |
| An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion JD Klement, AV Paschall, PS Redd, ML Ibrahim, C Lu, D Yang, E Celis, ... The Journal of clinical investigation 128 (12), 5549-5560, 2018 | 212 | 2018 |
| JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer C Lu, A Talukder, NM Savage, N Singh, K Liu Oncoimmunology 6 (3), e1291106, 2017 | 144 | 2017 |
| UFBP1, a key component of the Ufm1 conjugation system, is essential for ufmylation-mediated regulation of erythroid development Y Cai, W Pi, S Sivaprakasam, X Zhu, M Zhang, J Chen, L Makala, C Lu, ... PLoS genetics 11 (11), e1005643, 2015 | 135 | 2015 |
| Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes C Lu, JD Klement, ML Ibrahim, W Xiao, PS Redd, A Nayak-Kapoor, ... Journal for immunotherapy of cancer 7 (1), 1-11, 2019 | 109 | 2019 |
| H3K9 trimethylation silences Fas expression to confer colon carcinoma immune escape and 5-fluorouracil chemoresistance AV Paschall, D Yang, C Lu, JH Choi, X Li, F Liu, M Figueroa, NH Oberlies, ... The Journal of Immunology 195 (4), 1868-1882, 2015 | 108 | 2015 |
| Osteopontin: a key regulator of tumor progression and immunomodulation HR Moorman, D Poschel, JD Klement, C Lu, PS Redd, K Liu Cancers 12 (11), 3379, 2020 | 93 | 2020 |
| Myeloid-derived suppressor cells produce IL-10 to elicit DNMT3b-dependent IRF8 silencing to promote colitis-associated colon tumorigenesis ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, ... Cell reports 25 (11), 3036-3046. e6, 2018 | 84 | 2018 |
| Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells F Liu, X Li, C Lu, A Bai, J Bielawski, A Bielawska, B Marshall, ... Oncotarget 7 (51), 83907, 2016 | 84 | 2016 |
| IFNAR1 controls autocrine type I IFN regulation of PD-L1 expression in myeloid-derived suppressor cells W Xiao, JD Klement, C Lu, ML Ibrahim, K Liu The Journal of Immunology 201 (1), 264-277, 2018 | 74 | 2018 |
| The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription PS Simon, SK Sharman, C Lu, D Yang, AV Paschall, SS Tulachan, K Liu BMC cancer 15, 1-12, 2015 | 71 | 2015 |
| Alteration of tumor metabolism by CD4+ T cells leads to TNF-α-dependent intensification of oxidative stress and tumor cell death T Habtetsion, ZC Ding, W Pi, T Li, C Lu, T Chen, C Xi, H Spartz, K Liu, ... Cell metabolism 28 (2), 228-242. e6, 2018 | 65 | 2018 |
| Asah2 represses the p53–Hmox1 axis to protect myeloid-derived suppressor cells from ferroptosis H Zhu, JD Klement, C Lu, PS Redd, D Yang, AD Smith, DB Poschel, J Zou, ... The Journal of Immunology 206 (6), 1395-1404, 2021 | 58 | 2021 |
| Autocrine IL6-mediated activation of the STAT3–DNMT axis silences the TNFα–RIP1 necroptosis pathway to sustain survival and accumulation of myeloid-derived suppressor cells AD Smith, C Lu, D Payne, AV Paschall, JD Klement, PS Redd, ML Ibrahim, ... Cancer research 80 (15), 3145-3156, 2020 | 57 | 2020 |
| The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins S Wei, H Wang, C Lu, S Malmut, J Zhang, S Ren, G Yu, W Wang, ... Journal of Biological Chemistry 289 (13), 8947-8959, 2014 | 57 | 2014 |
| Targeting translation: eIF4E as an emerging anticancer drug target C Lu, L Makala, D Wu, Y Cai Expert reviews in molecular medicine 18, e2, 2016 | 54 | 2016 |
| Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation Y Cai, G Zhu, S Liu, Z Pan, M Quintero, CJ Poole, C Lu, H Zhu, B Islam, ... Cell Discovery 5 (1), 7, 2019 | 51 | 2019 |
| Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells C Lu, D Yang, ME Sabbatini, AH Colby, MW Grinstaff, NH Oberlies, ... BMC cancer 18, 1-12, 2018 | 48 | 2018 |
| SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion C Lu, D Yang, JD Klement, IK Oh, NM Savage, JL Waller, AH Colby, ... Cancer immunology research 7 (3), 414-427, 2019 | 47 | 2019 |
John D KlementInternal Medicine PGY-2, StanfordVerified email at stanford.edu
