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Resat Cinar
Resat Cinar
National Institute on Alcohol Abuse and Alcoholism / National Institutes of Health
Dirección de correo verificada de nih.gov
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Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
T Jourdan, G Godlewski, R Cinar, A Bertola, G Szanda, J Liu, J Tam, ...
Nature medicine 19 (9), 1132-1140, 2013
3932013
Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance
J Tam, R Cinar, J Liu, G Godlewski, D Wesley, T Jourdan, G Szanda, ...
Cell metabolism 16 (2), 167-179, 2012
3492012
Crystal structure of the human cannabinoid receptor CB2
X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ...
Cell 176 (3), 459-467. e13, 2019
3452019
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
O Gunduz-Cinar, KP MacPherson, R Cinar, J Gamble-George, K Sugden, ...
Molecular psychiatry 18 (7), 813-823, 2013
3382013
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy
M Rajesh, S Bátkai, M Kechrid, P Mukhopadhyay, WS Lee, B Horváth, ...
Diabetes 61 (3), 716-727, 2012
2672012
Endocannabinoids in liver disease
J Tam, J Liu, B Mukhopadhyay, R Cinar, G Godlewski, G Kunos
Hepatology 53 (1), 346-355, 2011
2272011
Chronic alcohol produces neuroadaptations to prime dorsal striatal learning
L DePoy, R Daut, JL Brigman, K MacPherson, N Crowley, ...
Proceedings of the National Academy of Sciences 110 (36), 14783-14788, 2013
2002013
Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides
R Cinar, G Godlewski, J Liu, J Tam, T Jourdan, B Mukhopadhyay, ...
Hepatology 59 (1), 143-153, 2014
1612014
Stratification of hepatocellular carcinoma patients based on acetate utilization
E Björnson, B Mukhopadhyay, A Asplund, N Pristovsek, R Cinar, ...
Cell reports 13 (9), 2014-2026, 2015
1352015
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy
T Jourdan, G Szanda, AZ Rosenberg, J Tam, BJ Earley, G Godlewski, ...
Proceedings of the National Academy of Sciences 111 (50), E5420-E5428, 2014
1322014
Network analyses identify liver‐specific targets for treating liver diseases
S Lee, C Zhang, Z Liu, M Klevstig, B Mukhopadhyay, M Bergentall, ...
Molecular systems biology 13 (8), 938, 2017
1202017
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver
B Mukhopadhyay, R Cinar, S Yin, J Liu, J Tam, G Godlewski, ...
Proceedings of the National Academy of Sciences 108 (15), 6323-6328, 2011
1062011
The therapeutic potential of second and third generation CB1R antagonists
R Cinar, MR Iyer, G Kunos
Pharmacology & therapeutics 208, 107477, 2020
1052020
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects
G Godlewski, SO Alapafuja, S Bátkai, SP Nikas, R Cinar, L Offertáler, ...
Chemistry & biology 17 (11), 1256-1266, 2010
982010
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms
B Mukhopadhyay, K Schuebel, P Mukhopadhyay, R Cinar, G Godlewski, ...
Hepatology 61 (5), 1615-1626, 2015
932015
β‐Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice
ZV Varga, C Matyas, K Erdelyi, R Cinar, D Nieri, A Chicca, BT Nemeth, ...
British journal of pharmacology 175 (2), 320-334, 2018
892018
Proximal tubular cannabinoid-1 receptor regulates obesity-induced CKD
S Udi, L Hinden, B Earley, A Drori, N Reuveni, R Hadar, R Cinar, ...
Journal of the American Society of Nephrology 28 (12), 3518-3532, 2017
882017
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase
J Liu, R Cinar, K Xiong, G Godlewski, T Jourdan, Y Lin, JM Ntambi, ...
Proceedings of the National Academy of Sciences 110 (47), 18832-18837, 2013
822013
National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-Host disease: IV. the 2020 highly morbid forms report
D Wolff, V Radojcic, R Lafyatis, R Cinar, RK Rosenstein, EW Cowen, ...
Transplantation and cellular therapy 27 (10), 817-835, 2021
792021
The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI‐101 prevents cisplatin‐induced nephrotoxicity
P Mukhopadhyay, M Baggelaar, K Erdelyi, Z Cao, R Cinar, F Fezza, ...
British journal of pharmacology 173 (3), 446-458, 2016
762016
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Artículos 1–20