Ismael Santa-Maria
Ismael Santa-Maria
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Primary age-related tauopathy (PART): a common pathology associated with human aging
JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ...
Acta neuropathologica 128, 755-766, 2014
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
I Santa-Maria, ME Alaniz, N Renwick, C Cela, TA Fulga, D Van Vactor, ...
The Journal of clinical investigation 125 (2), 681-686, 2015
Tau–an inhibitor of deacetylase HDAC6 function
M Perez, I Santa‐Maria, EG De Barreda, X Zhu, R Cuadros, JR Cabrero, ...
Journal of neurochemistry 109 (6), 1756-1766, 2009
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors
AA Sproul, S Jacob, D Pre, SH Kim, MW Nestor, M Navarro-Sobrino, ...
PloS one 9 (1), e84547, 2014
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease
S Mondragón‐Rodríguez, G Basurto‐Islas, I Santa‐Maria, R Mena, ...
International journal of experimental pathology 89 (2), 81-90, 2008
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes
I Santa-Maria, M Varghese, H Ksiȩżak-Reding, A Dzhun, J Wang, ...
Journal of Biological Chemistry 287 (24), 20522-20533, 2012
Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease
J Wang, I Santa-Maria, L Ho, H Ksiezak-Reding, K Ono, DB Teplow, ...
Journal of Alzheimer's Disease 22 (2), 653-661, 2010
Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau
I Santa-Maria, F Hernández, J Del Rio, FJ Moreno, J Avila
Molecular neurodegeneration 2, 1-12, 2007
The MAPT H1 haplotype is associated with tangle-predominant dementia
I Santa-Maria, A Haggiagi, X Liu, J Wasserscheid, PT Nelson, K Dewar, ...
Acta neuropathologica 124, 693-704, 2012
Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols
H Ksiezak-Reding, L Ho, I Santa-Maria, C Diaz-Ruiz, J Wang, ...
Neurobiology of aging 33 (7), 1427-1439, 2012
Tau phosphorylation, aggregation, and cell toxicity
J Avila, I Santa-Maria, M Perez, F Hernandez, F Moreno
BioMed Research International 2006 (1), 074539, 2006
Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase
C Boland, P Hayes, I Santa-Maria, S Nishimura, VP Kelly
Journal of Biological Chemistry 284 (27), 18218-18227, 2009
Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-β-peptide aggregation
I Santa-María, F Hernández, FJ Moreno, J Avila
Neuroscience letters 429 (2-3), 91-94, 2007
Binding of Hsp90 to tau promotes a conformational change and aggregation of tau protein
E Tortosa, I Santa-Maria, F Moreno, F Lim, M Perez, J Avila
Journal of Alzheimer's Disease 17 (2), 319-325, 2009
GSPE interferes with tau aggregation in vivo: implication for treating tauopathy
I Santa-Maria, C Diaz-Ruiz, H Ksiezak-Reding, A Chen, L Ho, J Wang, ...
Neurobiology of aging 33 (9), 2072-2081, 2012
Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers
I Santa-María, F Hernández, CP Martín, J Avila, FJ Moreno
Biochemistry 43 (10), 2888-2897, 2004
Characteristics of the binding of thioflavin S to tau paired helical filaments
I Santa-María, M Pérez, F Hernández, J Avila, FJ Moreno
Journal of Alzheimer's Disease 9 (3), 279-285, 2006
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease
I Santa-María, MA Smith, G Perry, F Hernández, J Avila, FJ Moreno
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1740 (3), 472-480, 2005
Development of a grape seed polyphenolic extract with anti‐oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies
GM Pasinetti, H Ksiezak‐Reding, I Santa‐Maria, J Wang, L Ho
Journal of neurochemistry 114 (6), 1557-1568, 2010
Assembly in vitro of tau protein and its implications in Alzheimer's disease
J Avila, M Pérez, JJ Lucas, A Gómez-Ramos, IS Maria, F Moreno, M Smith, ...
Current Alzheimer Research 1 (2), 97-101, 2004
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