Kevin Gorski
Kevin Gorski
Dirección de correo verificada de amgen.com
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B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
KS Gorski*, M Tseng*, Su-Yi, Otsuji*, X Huang, JE Slansky, SI Pai, ...
The Journal of experimental medicine 193 (7), 839-846, 2001
9912001
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
KB Gorden, KS Gorski, SJ Gibson, RM Kedl, WC Kieper, X Qiu, MA Tomai, ...
The Journal of Immunology 174 (3), 1259-1268, 2005
7202005
Oncolytic virotherapy promotes intratumoral T cell infiltration and improves anti-PD-1 immunotherapy
A Ribas, R Dummer, I Puzanov, A VanderWalde, RHI Andtbacka, ...
Cell 170 (6), 1109-1119. e10, 2017
6802017
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses
GM Gauvreau, PM O'Byrne, LP Boulet, Y Wang, D Cockcroft, J Bigler, ...
N Engl J Med 370, 2102-2110, 2014
6602014
Talimogene laherparepvec in combination with ipilimumab in previously untreated, unresectable stage IIIB-IV melanoma
I Puzanov, MM Milhem, D Minor, O Hamid, A Li, L Chen, M Chastain, ...
Journal of Clinical Oncology 34 (22), 2619, 2016
3422016
Cutting edge: expression of functional CD137 receptor by dendritic cells
RA Wilcox, AI Chapoval, KS Gorski, M Otsuji, T Shin, DB Flies, K Tamada, ...
The Journal of Immunology 168 (9), 4262-4267, 2002
2982002
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.
AW Tolcher, J Sarantopoulos, A Patnaik, K Papadopoulos, CC Lin, ...
Clin Oncol 25, 1390, 2007
2972007
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor
T Shin, G Kennedy, KS Gorski, H Tsuchiya, H Koseki, M Azuma, H Yagita, ...
The Journal of experimental medicine 198 (1), 31-38, 2003
2032003
Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists
KS Gorski, EL Waller, J Bjornton-Severson, JA Hanten, CL Riter, ...
International immunology 18 (7), 1115-1126, 2006
1552006
Selective modulation of TLR-mediated biological activity
JR Fink, KB Gorden, KS Gorski, SK Gupta, X Qiu, JP Vasilakos
US Patent 7,485,432, 2009
1342009
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer
AZ Dudek, C Yunis, LI Harrison, S Kumar, R Hawkinson, S Cooley, ...
Clinical Cancer Research 13 (23), 7119-7125, 2007
1222007
Efficacy analysis of MASTERKEY-265 phase 1b study of talimogene laherparepvec (T-VEC) and pembrolizumab (pembro) for unresectable stage IIIB-IV melanoma.
GV Long, R Dummer, A Ribas, I Puzanov, A VanderWalde, ...
Journal of Clinical Oncology 34 (15_suppl), 9568-9568, 2016
1022016
Primary analysis of a phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (ipi) in previously untreated, unresected …
I Puzanov, MM Milhem, RHI Andtbacka, DR Minor, O Hamid, A Li, ...
Journal of Clinical Oncology 32 (15_suppl), 9029-9029, 2014
902014
Immunotherapy of established tumors using bone marrow transplantation with antigen gene–modified hematopoietic stem cells
Y Cui, E Kelleher, E Straley, E Fuchs, KS Gorski, H Levitsky, I Borrello, ...
Nature medicine 9 (7), 952-958, 2003
722003
Oncolytic virotherapy promotes intratumoral T cell infiltration and improves anti-PD-1 immunotherapy
A Ribas, R Dummer, I Puzanov, A VanderWalde, RHI Andtbacka, ...
Cell 174 (4), 1031-1032, 2018
652018
B7-DC, Dendritic cell co-stimulatory molecules
DM Pardoll, H Tsuchiya, KS Gorski, S Tseng
US Patent 7,030,219, 2006
56*2006
Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors
T Doi, H Murakami, A Ohtsu, N Fuse, T Yoshino, N Yamamoto, N Boku, ...
Cancer chemotherapy and pharmacology 68 (3), 733-741, 2011
522011
Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation
KA Whartenby, EE Straley, H Kim, F Racke, V Tanavde, KS Gorski, ...
Blood, The Journal of the American Society of Hematology 100 (9), 3147-3154, 2002
482002
Homeostasis of human NK cells is not IL-15 dependent
H Lebrec, MJ Horner, KS Gorski, W Tsuji, D Xia, WJ Pan, G Means, ...
The Journal of Immunology 191 (11), 5551-5558, 2013
462013
Evidence for four distinct major protein components in the paraflagellar rod of Trypanosoma cruzi
DL Fouts, GA Stryker, KS Gorski, MJ Miller, TV Nguyen, RA Wrightsman, ...
Journal of Biological Chemistry 273 (34), 21846-21855, 1998
411998
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Artículos 1–20