The facile dealkylation of phosphonic acid dialkyl esters by bromotrimethylsilane CE Mckenna, MT Higa, NH Cheung, MC McKenna Tetrahedron Letters 18 (2), 155-158, 1977 | 550 | 1977 |
The relationship between the chemistry and biological activity of the bisphosphonates FH Ebetino, AML Hogan, S Sun, MK Tsoumpra, X Duan, JT Triffitt, ... Bone 49 (1), 20-33, 2011 | 487 | 2011 |
Synthesis, biological evaluation, and quantitative structure− activity relationship analysis of new Schiff bases of hydroxysemicarbazide as potential antitumor agents S Ren, R Wang, K Komatsu, P Bonaz-Krause, Y Zyrianov, CE McKenna, ... Journal of medicinal chemistry 45 (2), 410-419, 2002 | 399 | 2002 |
Bromodomains: Structure, function and pharmacology of inhibition E Ferri, C Petosa, CE McKenna Biochemical pharmacology 106, 1-18, 2016 | 266 | 2016 |
Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo AJ Roelofs, FP Coxon, FH Ebetino, MW Lundy, ZJ Henneman, ... Journal of Bone and Mineral Research 25 (3), 606-616, 2010 | 192 | 2010 |
Functional selectivity in phosphonate ester dealkylation with bromotrimethylsilane CE McKenna, J Schmidhuser Journal of the Chemical Society, Chemical Communications, 739-739, 1979 | 190 | 1979 |
Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer S Junankar, G Shay, J Jurczyluk, N Ali, J Down, N Pocock, A Parker, ... Cancer discovery 5 (1), 35-42, 2015 | 154 | 2015 |
Fluorination of methanediphosphonate esters by perchloryl fluoride. Synthesis of fluoromethanediphosphonic acid and difluoromethanediphosphonic acid CE McKenna, PD Shen The Journal of Organic Chemistry 46 (22), 4573-4576, 1981 | 147 | 1981 |
Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo FP Coxon, FH Ebetino, EH Mules, MC Seabra, CE McKenna, MJ Rogers Bone 37 (3), 349-358, 2005 | 122 | 2005 |
Modifying the β, γ leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase β CA Sucato, TG Upton, BA Kashemirov, VK Batra, V Martínek, Y Xiang, ... Biochemistry 46 (2), 461-471, 2007 | 120 | 2007 |
Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo AJ Roelofs, CA Stewart, S Sun, KM Błażewska, BA Kashemirov, ... Journal of bone and mineral research 27 (4), 835-847, 2012 | 119 | 2012 |
RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation X Tian, RU Jin, AJ Bredemeyer, EJ Oates, KM Błażewska, CE McKenna, ... Molecular and cellular biology 30 (5), 1269-1284, 2010 | 110 | 2010 |
Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: role in osteoclast-mediated NK cell activation HC Tseng, K Kanayama, K Kaur, SH Park, S Park, A Kozlowska, S Sun, ... Oncotarget 6 (24), 20002, 2015 | 107 | 2015 |
Circular dichroism and magnetic circular dichroism of nitrogenase proteins PJ Stephens, CE McKenna, BE Smith, HT Nguyen, MC McKenna, ... Proceedings of the National Academy of Sciences 76 (6), 2585-2589, 1979 | 107 | 1979 |
Synthesis and biological evaluation of α-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate MS Marma, Z Xia, C Stewart, F Coxon, JE Dunford, R Baron, ... Journal of medicinal chemistry 50 (24), 5967-5975, 2007 | 102 | 2007 |
Design, synthesis, and antimicrobial evaluation of a novel bone-targeting bisphosphonate-ciprofloxacin conjugate for the treatment of osteomyelitis biofilms PP Sedghizadeh, S Sun, AF Junka, E Richard, K Sadrerafi, S Mahabady, ... Journal of medicinal chemistry 60 (6), 2326-2343, 2017 | 100 | 2017 |
The vanadium effect in nitrogen fixation by azotobacter JR Benemann, CE McKenna, RF Lie, TG Traylor, MD Kamen Biochimica et Biophysica Acta (BBA)-General Subjects 264 (1), 25-38, 1972 | 99 | 1972 |
DNA polymerase β fidelity: Halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state CA Sucato, TG Upton, BA Kashemirov, J Osuna, K Oertell, WA Beard, ... Biochemistry 47 (3), 870-879, 2008 | 97 | 2008 |
Tungsten incorporation into Azotobacter vinelandii nitrogenase JR Benemann, GM Smith, PJ Kostel, CE McKenna FEBS letters 29 (3), 219-221, 1973 | 92 | 1973 |
A method for preparing analytically pure sodium dithionite. Dithionite quality and observed nitrogenase-specific activities CE McKenna, WG Gutheil, W Song Biochimica et Biophysica Acta (BBA)-General Subjects 1075 (1), 109-117, 1991 | 91 | 1991 |