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Luis A. Diaz Jr.
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Year
PD-1 blockade in tumors with mismatch-repair deficiency
DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ...
New England Journal of Medicine 372 (26), 2509-2520, 2015
100052015
Cancer genome landscapes
B Vogelstein, N Papadopoulos, VE Velculescu, S Zhou, LA Diaz Jr, ...
science 339 (6127), 1546-1558, 2013
89262013
An integrated genomic analysis of human glioblastoma multiforme
DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1807-1812, 2008
70462008
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ...
Science 357 (6349), 409-413, 2017
64402017
Detection of circulating tumor DNA in early-and late-stage human malignancies
C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ...
Science translational medicine 6 (224), 224ra24-224ra24, 2014
50152014
Circulating mutant DNA to assess tumor dynamics
F Diehl, K Schmidt, MA Choti, K Romans, S Goodman, M Li, K Thornton, ...
Nature medicine 14 (9), 985-990, 2008
30662008
Detection and localization of surgically resectable cancers with a multi-analyte blood test
JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ...
Science 359 (6378), 926-930, 2018
25892018
Efficacy of pembrolizumab in patients with noncolorectal high microsatellite instability/mismatch repair–deficient cancer: results from the phase II KEYNOTE-158 study
A Marabelle, DT Le, PA Ascierto, AM Di Giacomo, A De Jesus-Acosta, ...
Journal of Clinical Oncology 38 (1), 1-10, 2020
25232020
Liquid biopsies: genotyping circulating tumor DNA
LA Diaz Jr, A Bardelli
Journal of clinical oncology 32 (6), 579-586, 2014
24422014
Pembrolizumab in microsatellite-instability–high advanced colorectal cancer
T André, KK Shiu, TW Kim, BV Jensen, LH Jensen, C Punt, D Smith, ...
New England Journal of Medicine 383 (23), 2207-2218, 2020
22702020
Fulminant myocarditis with combination immune checkpoint blockade
DB Johnson, JM Balko, ML Compton, S Chalkias, J Gorham, Y Xu, ...
New England Journal of Medicine 375 (18), 1749-1755, 2016
21572016
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
LA Diaz Jr, RT Williams, J Wu, I Kinde, JR Hecht, J Berlin, B Allen, I Bozic, ...
Nature 486 (7404), 537-540, 2012
19892012
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
Y Jiao, C Shi, BH Edil, RF De Wilde, DS Klimstra, A Maitra, RD Schulick, ...
Science 331 (6021), 1199-1203, 2011
18962011
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
PJ Killela, ZJ Reitman, Y Jiao, C Bettegowda, N Agrawal, LA Diaz Jr, ...
Proceedings of the National Academy of Sciences 110 (15), 6021-6026, 2013
16052013
Detection and quantification of mutations in the plasma of patients with colorectal tumors
F Diehl, M Li, D Dressman, Y He, D Shen, S Szabo, LA Diaz Jr, ...
Proceedings of the National Academy of Sciences 102 (45), 16368-16373, 2005
15622005
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
S Jones, TL Wang, IM Shih, TL Mao, K Nakayama, R Roden, R Glas, ...
Science 330 (6001), 228-231, 2010
14652010
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer
J Tie, Y Wang, C Tomasetti, L Li, S Springer, I Kinde, N Silliman, M Tacey, ...
Science translational medicine 8 (346), 346ra92-346ra92, 2016
14512016
Immunotherapy in colorectal cancer: rationale, challenges and potential
K Ganesh, ZK Stadler, A Cercek, RB Mendelsohn, J Shia, NH Segal, ...
Nature reviews Gastroenterology & hepatology 16 (6), 361-375, 2019
14272019
Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations
DS Shin, JM Zaretsky, H Escuin-Ordinas, A Garcia-Diaz, S Hu-Lieskovan, ...
Cancer discovery 7 (2), 188-201, 2017
12192017
The colorectal microRNAome
JM Cummins, Y He, RJ Leary, R Pagliarini, LA Diaz Jr, T Sjoblom, ...
Proceedings of the National Academy of Sciences 103 (10), 3687-3692, 2006
12072006
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