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Benjamin J Schmiedel
Benjamin J Schmiedel
La Jolla Institute for Immunology (LJI)
Dirección de correo verificada de lji.org
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Impact of genetic polymorphisms on human immune cell gene expression
BJ Schmiedel, D Singh, A Madrigal, AG Valdovino-Gonzalez, BM White, ...
Cell 175 (6), 1701-1715. e16, 2018
6442018
Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis
VS Patil, A Madrigal, BJ Schmiedel, J Clarke, P O’Rourke, AD de Silva, ...
Science immunology 3 (19), eaan8664, 2018
2372018
CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells
T Baessler, JE Charton, BJ Schmiedel, F Grünebach, M Krusch, A Wacker, ...
Blood, The Journal of the American Society of Hematology 115 (15), 3058-3069, 2010
1522010
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma
G Seumois, C Ramírez-Suástegui, BJ Schmiedel, S Liang, B Peters, ...
Science immunology 5 (48), eaba6087, 2020
1302020
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
BJ Schmiedel, G Seumois, D Samaniego-Castruita, J Cayford, V Schulten, ...
Nature communications 7 (1), 13426, 2016
1112016
Glucocorticoid-induced tumor necrosis factor receptor–related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans
T Baessler, M Krusch, BJ Schmiedel, M Kloss, KM Baltz, A Wacker, ...
Cancer research 69 (3), 1037-1045, 2009
1022009
Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation
BJ Schmiedel, V Arélin, F Gruenebach, M Krusch, SM Schmidt, HR Salih
International journal of Cancer 128 (12), 2911-2922, 2011
912011
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia
BJ Schmiedel, CA Scheible, T Nuebling, HG Kopp, S Wirths, M Azuma, ...
Cancer research 73 (2), 683-694, 2013
792013
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants
V Chandra, S Bhattacharyya, BJ Schmiedel, A Madrigal, ...
Nature genetics 53 (1), 110-119, 2021
732021
4‐1BB ligand modulates direct and Rituximab‐induced NK‐cell reactivity in chronic lymphocytic leukemia
C Buechele, T Baessler, BJ Schmiedel, CE Schumacher, ...
European journal of immunology 42 (3), 737-748, 2012
662012
Glucocorticoid-induced TNFR-related protein (GITR) ligand modulates cytokine release and NK cell reactivity in chronic lymphocytic leukemia (CLL)
C Buechele, T Baessler, S Wirths, JU Schmohl, BJ Schmiedel, HR Salih
Leukemia 26 (5), 991-1000, 2012
642012
Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity
KM Baltz, M Krusch, T Baessler, BJ Schmiedel, A Bringmann, P Brossart, ...
Blood, The Journal of the American Society of Hematology 112 (9), 3735-3743, 2008
632008
The immune checkpoint modulator OX40 and its ligand OX40L in NK-cell immunosurveillance and acute myeloid leukemia
T Nuebling, CE Schumacher, M Hofmann, I Hagelstein, BJ Schmiedel, ...
Cancer Immunology Research 6 (2), 209-221, 2018
592018
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity
MND Svensson, KM Doody, BJ Schmiedel, S Bhattacharyya, B Panwar, ...
The Journal of Clinical Investigation 129 (3), 1193-1210, 2019
552019
Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis
J Wild, BJ Schmiedel, A Maurer, S Raab, L Prokop, S Stevanović, D Dörfel, ...
Leukemia 29 (8), 1676-1683, 2015
542015
Membrane‐associated phospholipase A1 beta (LIPI) is an Ewing tumour‐associated cancer/testis antigen
JL Foell, M Hesse, I Volkmer, BJ Schmiedel, I Neumann, MS Staege
Pediatric blood & cancer 51 (2), 228-234, 2008
532008
Fc-Optimized NKG2D–Fc constructs induce NK Cell antibody-dependent cellular cytotoxicity against breast cancer cells independently of HER2/neu expression status
S Raab, J Steinbacher, BJ Schmiedel, PC Kousis, A Steinle, G Jung, ...
The Journal of Immunology 193 (8), 4261-4272, 2014
472014
COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
BJ Schmiedel, J Rocha, C Gonzalez-Colin, S Bhattacharyya, A Madrigal, ...
Nature communications 12 (1), 6760, 2021
452021
An Fc‐optimized NKG2D‐immunoglobulin G fusion protein for induction of natural killer cell reactivity against leukemia
J Steinbacher, K Baltz‐Ghahremanpour, BJ Schmiedel, A Steinle, G Jung, ...
International journal of cancer 136 (5), 1073-1084, 2015
412015
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance
BJ Schmiedel, T Nuebling, J Steinbacher, A Malinovska, CM Wende, ...
The Journal of Immunology 190 (2), 821-831, 2013
382013
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