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Ashutosh Phadte
Ashutosh Phadte
Postdoctoral Research Fellow
Dirección de correo verificada de jefferson.edu
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Failure of oxysterols such as lanosterol to restore lens clarity from cataracts
DM Daszynski, P Santhoshkumar, AS Phadte, KK Sharma, HA Zhong, ...
Scientific reports 9 (1), 8459, 2019
522019
Therapeutic potential of α-crystallins in retinal neurodegenerative diseases
AS Phadte, ZB Sluzala, PE Fort
Antioxidants 10 (7), 1001, 2021
112021
Functional rescue of cataract-causing αA-G98R-crystallin by targeted compensatory suppressor mutations in human αA-crystallin
AS Phadte, S Mahalingam, P Santhoshkumar, KK Sharma
Biochemistry 58 (40), 4148-4158, 2019
62019
Characterization of an N-terminal mutant of αA-crystallin αA–R21Q associated with congenital cataract
AS Phadte, P Santhoshkumar, KK Sharma
Experimental eye research 174, 185-195, 2018
62018
Evidence for Paracrine Protective Role of Exogenous αA-Crystallin in Retinal Ganglion Cells
M Nath, ZB Sluzala, AS Phadte, Y Shan, AM Myers, PE Fort
Eneuro 9 (2), 2022
32022
αA-crystallin-derived minichaperone stabilizes αAG98R-crystallin by affecting its zeta potential
AS Phadte, P Santhoshkumar, KK Sharma
Molecular Vision 24, 297, 2018
32018
FAN1 removes triplet repeat extrusions via a PCNA-and RFC-dependent mechanism
AS Phadte, M Bhatia, H Ebert, H Abdullah, EA Elrazaq, KE Komolov, ...
Proceedings of the National Academy of Sciences 120 (33), e2302103120, 2023
22023
Mini-chaperone peptide binding sites in mutant αA-G98R protein and its efficacy to stabilize mutant protein in HLE-B3 cells
M Raju, P Santhoshkumar, A Phadte, KK Sharma
Investigative Ophthalmology & Visual Science 57 (12), 732-732, 2016
22016
T148 Phosphorylation on αA-crystallin Controls Functional and Structural Biochemical Properties
ZB Sluzala, A Phadte, PE Fort
Investigative Ophthalmology & Visual Science 62 (8), 1571-1571, 2021
2021
T148 Phosphorylation on αA-crystallin Impacts Functional and Structural Biochemical Properties
PE Fort, ZB Sluzala, A Phadte
Investigative Ophthalmology & Visual Science 61 (7), 743-743, 2020
2020
Retinal Müller Glial Cells Secreted αA-Crystallin is Protective to Retinal Neurons
M Nath, Y Shan, AM Myers, A Phadte, PE Fort
Investigative Ophthalmology & Visual Science 61 (7), 5128-5128, 2020
2020
Investigating the role of arginine 21 in the structure and function of human [alpha] A-crystallin
AS Phadte
University of Missouri--Columbia, 2018
2018
αA-crystallin derived mini chaperone stabilizes bovine γ-crystallin aggregation by affecting its zeta (ζ) potential.
A Phadte, P Santhoshkumar, KK Sharma
Investigative Ophthalmology & Visual Science 58 (8), 5299-5299, 2017
2017
LOSS OF FUNCTION IN αA-CRYSTALLIN MUTANT G98R IS RESCUED BY A COMPENSATORY MUTATION IN THE N-TERMINAL OF THE PROTEIN.
A Phadte, P Santhoshkumar, KK Sharma
Investigative Ophthalmology & Visual Science 57 (12), 728-728, 2016
2016
Characterization of a of αA crystallin mutant αAR21Q implicated in congenital cataract
AS Phadte, P Santhoshkumar, KK Sharma
Investigative Ophthalmology & Visual Science 56 (7), 5589-5589, 2015
2015
Erratum: Nath et al.,“Evidence for Paracrine Protective Role of Exogenous aA-Crystallin in Retinal Ganglion Cells”
ZB Sluzala, AS Phadte, Y Shan, AM Myers, PE Fort
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