| Identification and functional characterization of brainstem cannabinoid CB2 receptors MD Van Sickle, M Duncan, PJ Kingsley, A Mouihate, P Urbani, K Mackie, ... Science 310 (5746), 329-332, 2005 | 1874 | 2005 |
| Functional role of high-affinity anandamide transport, as revealed by selective inhibition M Beltramo, N Stella, A Calignano, SY Lin, A Makriyannis, D Piomelli Science 277 (5329), 1094-1097, 1997 | 1066 | 1997 |
| CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids MM Ibrahim, F Porreca, J Lai, PJ Albrecht, FL Rice, A Khodorova, G Davar, ... Proceedings of the National Academy of Sciences 102 (8), 3093-3098, 2005 | 673 | 2005 |
| Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS MM Ibrahim, H Deng, A Zvonok, DA Cockayne, J Kwan, HP Mata, ... Proceedings of the National Academy of Sciences 100 (18), 10529-10533, 2003 | 606 | 2003 |
| Structure− activity relationships of pyrazole derivatives as cannabinoid receptor antagonists R Lan, Q Liu, P Fan, S Lin, SR Fernando, D McCallion, R Pertwee, ... Journal of medicinal chemistry 42 (4), 769-776, 1999 | 575 | 1999 |
| Crystal structure of the human cannabinoid receptor CB1 T Hua, K Vemuri, M Pu, L Qu, GW Han, Y Wu, S Zhao, W Shui, S Li, ... Cell 167 (3), 750-762. e14, 2016 | 563 | 2016 |
| A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019 | 553 | 2019 |
| Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity J Tam, VK Vemuri, J Liu, S Bátkai, B Mukhopadhyay, G Godlewski, ... The Journal of clinical investigation 120 (8), 2953-2966, 2010 | 523 | 2010 |
| CB2 cannabinoid receptor-mediated peripheral antinociception TP Malan Jr, MM Ibrahim, H Deng, Q Liu, HP Mata, T Vanderah, F Porreca, ... Pain 93 (3), 239-245, 2001 | 511 | 2001 |
| Endocannabinoids control spasticity in a multiple sclerosis model D Baker, G Pryce, JL Croxford, P Brown, RG Pertwee, A Makriyannis, ... The FASEB journal 15 (2), 300-302, 2001 | 488 | 2001 |
| Crystal structures of agonist-bound human cannabinoid receptor CB1 T Hua, K Vemuri, SP Nikas, RB Laprairie, Y Wu, L Qu, M Pu, A Korde, ... Nature 547 (7664), 468-471, 2017 | 470 | 2017 |
| Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630 RA Ross, HC Brockie, LA Stevenson, VL Murphy, F Templeton, ... British journal of pharmacology 126 (3), 665, 1999 | 467 | 1999 |
| Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis S Bátkai, Z Járai, JA Wagner, SK Goparaju, KÁ Varga, J Liu, L Wang, ... Nature medicine 7 (7), 827-832, 2001 | 465 | 2001 |
| Functional CB1 cannabinoid receptors in human vascular endothelial cells J LIU, B GAO, F MIRSHAHI, AJ SANYAL, AD KHANOLKAR, ... Biochemical Journal 346 (3), 835-840, 2000 | 412 | 2000 |
| (R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability V Abadji, S Lin, G Taha, G Griffin, LA Stevenson, RG Pertwee, ... Journal of medicinal chemistry 37 (12), 1889-1893, 1994 | 368 | 1994 |
| Structural determinants for recognition and translocation by the anandamide transporter D Piomelli, M Beltramo, S Glasnapp, SY Lin, A Goutopoulos, XQ Xie, ... Proceedings of the National Academy of Sciences 96 (10), 5802-5807, 1999 | 366 | 1999 |
| Crystal structure of the human cannabinoid receptor CB2 X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ... Cell 176 (3), 459-467. e13, 2019 | 344 | 2019 |
| Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity O Gunduz-Cinar, KP MacPherson, R Cinar, J Gamble-George, K Sugden, ... Molecular psychiatry 18 (7), 813-823, 2013 | 338 | 2013 |
| 123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain cannabinoid CB1 receptors SJ Gatley, AN Gifford, ND Volkow, R Lan, A Makriyannis European journal of pharmacology 307 (3), 331-338, 1996 | 320 | 1996 |
| Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2Cannabinoid Receptors A Quartilho, HP Mata, MM Ibrahim, TW Vanderah, F Porreca, ... The Journal of the American Society of Anesthesiologists 99 (4), 955-960, 2003 | 299 | 2003 |
