Krzysztof Palczewski
Krzysztof Palczewski
UCI ophthalmology
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Crystal structure of rhodopsin: AG protein-coupled receptor
K Palczewski, T Kumasaka, T Hori, CA Behnke, H Motoshima, BA Fox, ...
science 289 (5480), 739-745, 2000
Rhodopsin dimers in native disc membranes
D Fotiadis, Y Liang, S Filipek, DA Saperstein, A Engel, K Palczewski
Nature 421 (6919), 127-128, 2003
G protein–coupled receptor rhodopsin
K Palczewski
Annu. Rev. Biochem. 75, 743-767, 2006
Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs),
DC Teller, T Okada, CA Behnke, K Palczewski, RE Stenkamp
Biochemistry 40 (26), 7761-7772, 2001
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
Y Liang, D Fotiadis, S Filipek, DA Saperstein, K Palczewski, A Engel
Journal of Biological Chemistry 278 (24), 21655-21662, 2003
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness
GM Acland, GD Aguirre, J Bennett, TS Aleman, AV Cideciyan, J Bennicelli, ...
Molecular Therapy 12 (6), 1072-1082, 2005
Activation of rhodopsin: new insights from structural and biochemical studies
T Okada, OP Ernst, K Palczewski, KP Hofmann
Trends in biochemical sciences 26 (5), 318-324, 2001
Phagocytosis of retinal rod and cone photoreceptors
BM Kevany, K Palczewski
Physiology 25 (1), 8-15, 2010
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
D Salom, DT Lodowski, RE Stenkamp, IL Trong, M Golczak, ...
Proceedings of the National Academy of Sciences 103 (44), 16123-16128, 2006
Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin
T Mirzadegan, G Benkö, S Filipek, K Palczewski
Biochemistry 42 (10), 2759-2767, 2003
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents
GH Travis, M Golczak, AR Moise, K Palczewski
Annu. Rev. Pharmacol. Toxicol. 47, 469-512, 2007
Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina
JK McBee, K Palczewski, W Baehr, DR Pepperberg
Progress in retinal and eye research 20 (4), 469-529, 2001
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation
O Fritze, S Filipek, V Kuksa, K Palczewski, KP Hofmann, OP Ernst
Proceedings of the National Academy of Sciences 100 (5), 2290-2295, 2003
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver
ML Batten, Y Imanishi, T Maeda, DC Tu, AR Moise, D Bronson, D Possin, ...
Journal of Biological Chemistry 279 (11), 10422-10432, 2004
Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein
K Palczewski, I Subbaraya, WA Gorczyca, BS Helekar, CC Ruiz, ...
Neuron 13 (2), 395-404, 1994
Turned on by Ca2+! The physiology and pathology of Ca2+-binding proteins in the retina
A Polans, W Baehr, K Palczewski
Trends in neurosciences 19 (12), 547-554, 1996
Chemistry of the retinoid (visual) cycle
PD Kiser, M Golczak, K Palczewski
Chemical reviews 114 (1), 194-232, 2014
Mechanism of rhodopsin kinase activation
K Palczewski, J Buczyłko, MW Kaplan, AS Polans, JW Crabb
Journal of Biological Chemistry 266 (20), 12949-12955, 1991
Retinoid absorption and storage is impaired in mice lacking lecithin: retinol acyltransferase (LRAT)
SM O'Byrne, N Wongsiriroj, J Libien, S Vogel, IJ Goldberg, W Baehr, ...
Journal of Biological Chemistry 280 (42), 35647-35657, 2005
Chemistry and biology of vision
K Palczewski
Journal of Biological Chemistry 287 (3), 1612-1619, 2012
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