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Benjamin Steinhorn
Benjamin Steinhorn
Massachusetts General Hospital
Dirección de correo verificada de mit.edu
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Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction
B Steinhorn, A Sorrentino, S Badole, Y Bogdanova, V Belousov, T Michel
Nature communications 9 (1), 4044, 2018
1022018
Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods
E Eroglu, SSS Saravi, A Sorrentino, B Steinhorn, T Michel
Proceedings of the National Academy of Sciences 116 (40), 20210-20217, 2019
562019
Nitroglycerin and nitric oxide—a rondo of themes in cardiovascular therapeutics
BS Steinhorn, J Loscalzo, T Michel
New England Journal of Medicine 373 (3), 277-280, 2015
542015
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
V Montiel, R Bella, LYM Michel, H Esfahani, D De Mulder, EL Robinson, ...
Science translational medicine 12 (564), eaay2176, 2020
532020
Which Antioxidant System Shapes Intracellular H2O2 Gradients?
NM Mishina, YA Bogdanova, YG Ermakova, AS Panova, DA Kotova, ...
Antioxidants & Redox Signaling 31 (9), 664-670, 2019
532019
Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4
B Steinhorn, JL Sartoretto, A Sorrentino, N Romero, H Kalwa, ED Abel, ...
Free Radical Biology and Medicine 113, 16-25, 2017
392017
Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis
SSS Saravi, E Eroglu, M Waldeck-Weiermair, A Sorrentino, B Steinhorn, ...
Redox biology 36, 101605, 2020
282020
Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress
A Sorrentino, B Steinhorn, L Troncone, SSS Saravi, S Badole, E Eroglu, ...
American Journal of Physiology-Heart and Circulatory Physiology 317 (3 …, 2019
262019
Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium
H Kalwa, JL Sartoretto, R Martinelli, N Romero, BS Steinhorn, M Tao, ...
Proceedings of the National Academy of Sciences 111 (9), 3383-3388, 2014
262014
Metabolomic and transcriptomic signatures of chemogenetic heart failure
F Spyropoulos, A Sorrentino, J van der Reest, P Yang, ...
American Journal of Physiology-Heart and Circulatory Physiology 322 (3 …, 2022
202022
Lipid emulsion rapidly restores contractility in stunned mouse cardiomyocytes: a comparison with therapeutic hypothermia
J Li, M Fettiplace, SJ Chen, B Steinhorn, Z Shao, X Zhu, C Li, S Harty, ...
Critical care medicine 42 (12), e734-e740, 2014
172014
A Comprehensive X-Ray and Multiwavelength Study of the Colliding Galaxy Pair NGC 2207/IC 2163
S Mineo, S Rappaport, A Levine, D Pooley, B Steinhorn, J Homan
The Astrophysical Journal 797 (2), 91, 2014
162014
Spatially Resolved Star Formation Image and the Ultraluminous X-Ray Source Population in NGC 2207/IC 2163
S Mineo, S Rappaport, B Steinhorn, A Levine, M Gilfanov, D Pooley
The Astrophysical Journal 771 (2), 133, 2013
162013
Ultraluminous X-ray Sources in Arp 147
S Rappaport, A Levine, D Pooley, B Steinhorn
The Astrophysical Journal 721 (2), 1348, 2010
142010
Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting
YC Erdogan, HY Altun, M Secilmis, BN Ata, G Sevimli, Z Cokluk, AG Zaki, ...
Free Radical Biology and Medicine 177, 132-142, 2021
132021
Chemogenetic approaches to probe redox pathways: implications for cardiovascular pharmacology and toxicology
B Steinhorn, E Eroglu, T Michel
Annual review of pharmacology and toxicology 62, 551-571, 2022
102022
Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction, Nat. Commun.(2018)
B Steinhorn, A Sorrentino, S Badole, Y Bogdanova, V Belousov, T Michel
8
Dose-dependent relationship between SGLT2 inhibitor hold time and risk for postoperative anion gap acidosis: a single-centre retrospective analysis
B Steinhorn, J Wiener-Kronish
British journal of anaesthesia 131 (4), 682-686, 2023
62023
Sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress in chemogenetic transgenic mouse lines
S Yadav, M Waldeck-Weiermair, F Spyropoulos, R Bronson, AK Pandey, ...
Nature Communications 14 (1), 3094, 2023
62023
35 Cardiac aquaporin-1 mediates transmembrane transport of hydrogen peroxide and modulates myocardial fibrosis and hypertrophic remodeling
V Montiel, H Esfahani, D De Mulder, JP Deglasse, JC Jonas, B Steinhorn, ...
Cardiovascular Research 114 (suppl_1), S9-S9, 2018
42018
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Artículos 1–20