| Whole-exome sequencing of metastatic cancer and biomarkers of treatment response H Beltran, K Eng, JM Mosquera, A Sigaras, A Romanel, H Rennert, ... JAMA oncology 1 (4), 466-474, 2015 | 306 | 2015 |
| Artificial intelligence in cancer research and precision medicine B Bhinder, C Gilvary, NS Madhukar, O Elemento Cancer discovery 11 (4), 900-915, 2021 | 281 | 2021 |
| A data-driven approach to predicting successes and failures of clinical trials KM Gayvert, NS Madhukar, O Elemento Cell chemical biology 23 (10), 1294-1301, 2016 | 238 | 2016 |
| A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product MV Liberti, Z Dai, SE Wardell, JA Baccile, X Liu, X Gao, R Baldi, ... Cell metabolism 26 (4), 648-659. e8, 2017 | 193 | 2017 |
| A Bayesian machine learning approach for drug target identification using diverse data types NS Madhukar, PK Khade, L Huang, K Gayvert, G Galletti, M Stogniew, ... Nature communications 10 (1), 5221, 2019 | 184 | 2019 |
| Discovery and clinical introduction of first-in-class imipridone ONC201 JE Allen, CLB Kline, VV Prabhu, J Wagner, J Ishizawa, N Madhukar, ... Oncotarget 7 (45), 74380, 2016 | 141 | 2016 |
| The missing pieces of artificial intelligence in medicine C Gilvary, N Madhukar, J Elkhader, O Elemento Trends in pharmacological sciences 40 (8), 555-564, 2019 | 72 | 2019 |
| Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia T Nii, VV Prabhu, V Ruvolo, N Madhukar, R Zhao, H Mu, L Heese, ... Leukemia 33 (12), 2805-2816, 2019 | 58 | 2019 |
| Dopamine receptor D5 is a modulator of tumor response to dopamine receptor D2 antagonism VV Prabhu, NS Madhukar, C Gilvary, CLB Kline, S Oster, WS El-Deiry, ... Clinical Cancer Research 25 (7), 2305-2313, 2019 | 56 | 2019 |
| Organization of enzyme concentration across the metabolic network in cancer cells NS Madhukar, MO Warmoes, JW Locasale PloS one 10 (1), e0117131, 2015 | 48 | 2015 |
| Prediction of genetic interactions using machine learning and network properties NS Madhukar, O Elemento, G Pandey Frontiers in bioengineering and biotechnology 3, 172, 2015 | 42 | 2015 |
| Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors VV Prabhu, AR Lulla, NS Madhukar, MD Ralff, D Zhao, CLB Kline, ... PLoS One 12 (8), e0180541, 2017 | 40 | 2017 |
| Artificial intelligence in cancer research and precision medicine. Cancer Discov. 2021; 11: 900–915. doi: 10.1158/2159-8290 B Bhinder, C Gilvary, NS Madhukar, O Elemento CD-21-0090.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 38 | |
| A new big-data paradigm for target identification and drug discovery NS Madhukar, PK Khade, L Huang, K Gayvert, G Galletti, M Stogniew, ... Biorxiv, 134973, 2017 | 17 | 2017 |
| A machine learning and network framework to discover new indications for small molecules C Gilvary, J Elkhader, N Madhukar, C Henchcliffe, MD Goncalves, ... PLoS computational biology 16 (8), e1008098, 2020 | 15 | 2020 |
| Bioinformatics approaches to predict drug responses from genomic sequencing NS Madhukar, O Elemento Cancer Systems Biology: Methods and Protocols, 277-296, 2018 | 15 | 2018 |
| Abstract LB-209: D2-like dopamine receptor antagonism by ONC201 identified by confluence of computational, receptor binding, and clinical studies NS Madhukar, O Elemento, CH Benes, MJ Garnett, M Stein, JR Bertino, ... Cancer Research 76 (14_Supplement), LB-209-LB-209, 2016 | 6 | 2016 |
| CLIP-170S is a microtubule+ TIP variant that confers resistance to taxanes by impairing drug-target engagement PV Thakkar, K Kita, U Del Castillo, G Galletti, N Madhukar, EV Navarro, ... Developmental cell 56 (23), 3264-3275. e7, 2021 | 5 | 2021 |
| A machine learning approach predicts essential genes and pharmacological targets in cancer C Gilvary, NS Madhukar, K Gayvert, M Foronda, A Perez, CS Leslie, ... BioRxiv, 692277, 2019 | 5 | 2019 |
| A machine learning approach predicts tissue-specific drug adverse events NS Madhukar, K Gayvert, C Gilvary, O Elemento bioRxiv, 288332, 2018 | 5 | 2018 |
Olivier ElementoDirector, Englander Institute for Precision Medicine, Weill Cornell MedicineDirección de correo verificada de med.cornell.edu
