Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 395 | 2019 |
Spatiotemporal genomic architecture informs precision oncology in glioblastoma JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ... Nature genetics 49 (4), 594-599, 2017 | 269 | 2017 |
Mutational landscape of secondary glioblastoma guides MET-targeted trial in brain tumor H Hu, Q Mu, Z Bao, Y Chen, Y Liu, J Chen, K Wang, Z Wang, Y Nam, ... Cell 175 (6), 1665-1678. e18, 2018 | 265 | 2018 |
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy JK Lee, Z Liu, JK Sa, S Shin, J Wang, M Bordyuh, HJ Cho, O Elliott, T Chu, ... Nature genetics 50 (10), 1399-1411, 2018 | 172 | 2018 |
Determinants of response and intrinsic resistance to PD-1 blockade in microsatellite instability–high gastric cancer M Kwon, M An, SJ Klempner, H Lee, KM Kim, JK Sa, HJ Cho, JY Hong, ... Cancer discovery 11 (9), 2168-2185, 2021 | 139 | 2021 |
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang, M Galán-Ganga, ... Nature communications 11 (1), 3883, 2020 | 133 | 2020 |
A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma JM Barnes, S Kaushik, RO Bainer, JK Sa, EC Woods, FB Kai, L Przybyla, ... Nature cell biology 20 (10), 1203-1214, 2018 | 120 | 2018 |
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages J Yin, SS Kim, E Choi, YT Oh, W Lin, TH Kim, JK Sa, JH Hong, SH Park, ... Nature Communications 11 (1), 2978, 2020 | 97 | 2020 |
Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma JK Sa, N Chang, HW Lee, HJ Cho, M Ceccarelli, L Cerulo, J Yin, SS Kim, ... Genome biology 21, 1-17, 2020 | 82 | 2020 |
Transglutaminase 2 inhibition reverses mesenchymal transdifferentiation of glioma stem cells by regulating C/EBPβ signaling J Yin, YT Oh, JY Kim, SS Kim, E Choi, TH Kim, JH Hong, N Chang, ... Cancer research 77 (18), 4973-4984, 2017 | 80 | 2017 |
Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities S Oh, J Yeom, HJ Cho, JH Kim, SJ Yoon, H Kim, JK Sa, S Ju, H Lee, ... Nature communications 11 (1), 3288, 2020 | 60 | 2020 |
The combination of neoantigen quality and T lymphocyte infiltrates identifies glioblastomas with the longest survival J Zhang, FP Caruso, JK Sa, S Justesen, DH Nam, P Sims, M Ceccarelli, ... Communications biology 2 (1), 135, 2019 | 56 | 2019 |
Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial JY Hong, HJ Cho, JK Sa, X Liu, SY Ha, T Lee, H Kim, W Kang, DH Sinn, ... Genome medicine 14, 1-15, 2022 | 40 | 2022 |
Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy DG Kim, KH Kim, YJ Seo, H Yang, EG Marcusson, E Son, K Lee, JK Sa, ... Oncotarget 7 (20), 29400, 2016 | 35 | 2016 |
Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model HY Jeon, SW Ham, JK Kim, X Jin, SY Lee, YJ Shin, CY Choi, JK Sa, ... Cell Death & Differentiation 26 (10), 2139-2156, 2019 | 34 | 2019 |
A Phase II Trial of Tipifarnib for Patients with Previously Treated, Metastatic Urothelial Carcinoma Harboring HRAS Mutations HW Lee, JK Sa, A Gualberto, C Scholz, HH Sung, BC Jeong, HY Choi, ... Clinical Cancer Research 26 (19), 5113-5119, 2020 | 33 | 2020 |
Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma HJ Cho, J Zhao, SW Jung, E Ladewig, DS Kong, YL Suh, Y Lee, D Kim, ... Neuro-oncology 21 (1), 47-58, 2019 | 33 | 2019 |
PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma YJ Shin, JK Sa, Y Lee, D Kim, N Chang, HJ Cho, M Son, MYT Oh, K Shin, ... Journal of Experimental Medicine 216 (5), 1120-1134, 2019 | 30 | 2019 |
Anti-SEMA3A antibody: a novel therapeutic agent to suppress glioblastoma tumor growth J Lee, YJ Shin, K Lee, HJ Cho, JK Sa, SY Lee, SH Kim, J Lee, Y Yoon, ... Cancer Research and Treatment: Official Journal of Korean Cancer Association …, 2018 | 25 | 2018 |
Genomic and transcriptomic characterization of skull base chordoma JK Sa, IH Lee, SD Hong, DS Kong, DH Nam Oncotarget 8 (1), 1321, 2017 | 25 | 2017 |