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Aldo A. Rodriguez-Menchaca
Aldo A. Rodriguez-Menchaca
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The molecular basis of chloroquine block of the inward rectifier Kir2. 1 channel
AA Rodríguez-Menchaca, RA Navarro-Polanco, T Ferrer-Villada, J Rupp, ...
Proceedings of the National Academy of Sciences 105 (4), 1364-1368, 2008
1552008
PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4–S5 linker
AA Rodriguez-Menchaca, SK Adney, QY Tang, XY Meng, ...
Proceedings of the National Academy of Sciences 109 (36), E2399-E2408, 2012
1002012
Dual Regulation of Voltage-Sensitive Ion Channels by PIP2
AA Rodríguez-Menchaca, SK Adney, L Zhou, DE Logothetis
Frontiers in pharmacology 3, 170, 2012
652012
A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2
A Rosenhouse-Dantsker, JL Sui, Q Zhao, R Rusinova, ...
Nature chemical biology 4 (10), 624-631, 2008
632008
Tamoxifen inhibits inward rectifier K+ 2. x family of inward rectifier channels by interfering with phosphatidylinositol 4, 5-bisphosphate-channel interactions
D Ponce-Balbuena, A López-Izquierdo, T Ferrer, ...
Journal of Pharmacology and Experimental Therapeutics 331 (2), 563-573, 2009
532009
Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4, 5-bisphosphate and Gβγ
W Deng, AN Bukiya, AA Rodríguez-Menchaca, Z Zhang, CM Baumgarten, ...
Journal of Biological Chemistry 287 (7), 4925-4935, 2012
422012
Block of HERG channels by berberine: mechanisms of voltage-and state-dependence probed with site-directed mutant channels
A Rodriguez-Menchaca, T Ferrer-Villada, J Lara, D Fernandez, ...
Journal of cardiovascular pharmacology 47 (1), 21-29, 2006
412006
Revealing the activation pathway for TMEM16A chloride channels from macroscopic currents and kinetic models
JA Contreras-Vite, S Cruz-Rangel, JJ De Jesús-Pérez, IAA Figueroa, ...
Pflügers Archiv-European Journal of Physiology 468, 1241-1257, 2016
342016
S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis
AA Rodriguez‐Menchaca, E Solis Jr, K Cameron, LJ De Felice
British journal of pharmacology 165 (8), 2749-2757, 2012
332012
Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and …
A Rosenhouse-Dantsker, S Noskov, H Han, SK Adney, QY Tang, ...
Journal of Biological Chemistry 287 (48), 40266-40278, 2012
28*2012
The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction
A López-Izquierdo, D Ponce-Balbuena, EG Moreno-Galindo, ...
Journal of cardiovascular pharmacology 57 (4), 407-415, 2011
282011
Extracellular protons enable activation of the calcium‐dependent chloride channel TMEM16A
S Cruz‐Rangel, JJ De Jesús‐Pérez, IA Aréchiga‐Figueroa, ...
The Journal of Physiology 595 (5), 1515-1531, 2017
272017
Inhibition of cardiac HERG potassium channels by antidepressant maprotiline
T Ferrer-Villada, RA Navarro-Polanco, AA Rodríguez-Menchaca, ...
European journal of pharmacology 531 (1-3), 1-8, 2006
252006
Regulation of Kv2. 1 channel inactivation by phosphatidylinositol 4, 5-bisphosphate
M Delgado-Ramírez, JJ De Jesús-Pérez, IA Aréchiga-Figueroa, J Arreola, ...
Scientific reports 8 (1), 1769, 2018
232018
Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels
A López-Izquierdo, IA Aréchiga-Figueroa, EG Moreno-Galindo, ...
Pflügers Archiv-European Journal of Physiology 462, 505-517, 2011
222011
Chloroquine inhibits tumor-related Kv10. 1 channel and decreases migration of MDA-MB-231 breast cancer cells in vitro
B Valdés-Abadía, R Morán-Zendejas, JM Rangel-Flores, ...
European Journal of Pharmacology 855, 262-266, 2019
212019
Chloroquine blocks the Kir4. 1 channels by an open-pore blocking mechanism
LG Marmolejo-Murillo, IA Aréchiga-Figueroa, EG Moreno-Galindo, ...
European journal of pharmacology 800, 40-47, 2017
192017
Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6. 2/SUR2A channels
D Ponce-Balbuena, AA Rodríguez-Menchaca, A López-Izquierdo, ...
Molecular pharmacology 82 (5), 803-813, 2012
172012
Kv1. 5 open channel block by the antiarrhythmic drug disopyramide: molecular determinants of block
IA Aréchiga, GF Barrio-Echavarria, AA Rodríguez-Menchaca, ...
Journal of pharmacological sciences 108 (1), 49-55, 2008
172008
Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism
A López-Izquierdo, D Ponce-Balbuena, T Ferrer, ...
European journal of pharmacology 638 (1-3), 33-41, 2010
162010
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