Membrane protein folding: beyond the two stage model DM Engelman, Y Chen, CN Chin, AR Curran, AM Dixon, AD Dupuy, ... FEBS letters 555 (1), 122-125, 2003 | 390 | 2003 |
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo OA Andreev, AD Dupuy, M Segala, S Sandugu, DA Serra, CO Chichester, ... Proceedings of the National Academy of Sciences 104 (19), 7893-7898, 2007 | 357 | 2007 |
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix YK Reshetnyak, OA Andreev, U Lehnert, DM Engelman Proceedings of the National Academy of Sciences 103 (17), 6460-6465, 2006 | 281 | 2006 |
A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers YK Reshetnyak, M Segala, OA Andreev, DM Engelman Biophysical journal 93 (7), 2363-2372, 2007 | 235 | 2007 |
Family of pH (low) insertion peptides for tumor targeting D Weerakkody, A Moshnikova, MS Thakur, V Moshnikova, J Daniels, ... Proceedings of the National Academy of Sciences 110 (15), 5834-5839, 2013 | 221 | 2013 |
A novel technology for the imaging of acidic prostate tumors by positron emission tomography AL Vavere, GB Biddlecombe, WM Spees, JR Garbow, D Wijesinghe, ... Cancer research 69 (10), 4510-4516, 2009 | 221 | 2009 |
Probe for the measurement of cell surface pH in vivo and ex vivo M Anderson, A Moshnikova, DM Engelman, YK Reshetnyak, OA Andreev Proceedings of the National Academy of Sciences 113 (29), 8177-8181, 2016 | 211 | 2016 |
Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane YK Reshetnyak, OA Andreev, M Segala, VS Markin, DM Engelman Proceedings of the National Academy of Sciences 105 (40), 15340-15345, 2008 | 201 | 2008 |
Decomposition of protein tryptophan fluorescence spectra into log-normal components. III. Correlation between fluorescence and microenvironment parameters of individual … YK Reshetnyak, Y Koshevnik, EA Burstein Biophysical journal 81 (3), 1735-1758, 2001 | 192 | 2001 |
Decomposition of protein tryptophan fluorescence spectra into log-normal components. II. The statistical proof of discreteness of tryptophan classes in proteins YK Reshetnyak, EA Burstein Biophysical journal 81 (3), 1710-1734, 2001 | 187 | 2001 |
pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path OA Andreev, AG Karabadzhak, D Weerakkody, GO Andreev, ... Proceedings of the National Academy of Sciences 107 (9), 4081-4086, 2010 | 184 | 2010 |
pHLIP peptide targets nanogold particles to tumors L Yao, J Daniels, A Moshnikova, S Kuznetsov, A Ahmed, DM Engelman, ... Proceedings of the National Academy of Sciences 110 (2), 465-470, 2013 | 175 | 2013 |
pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation M An, D Wijesinghe, OA Andreev, YK Reshetnyak, DM Engelman Proceedings of the National Academy of Sciences 107 (47), 20246-20250, 2010 | 171 | 2010 |
pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents OA Andreev, DM Engelman, YK Reshetnyak Molecular membrane biology 27 (7), 341-352, 2010 | 155 | 2010 |
Decomposition of protein tryptophan fluorescence spectra into log-normal components. I. Decomposition algorithms EA Burstein, SM Abornev, YK Reshetnyak Biophysical Journal 81 (3), 1699-1709, 2001 | 145 | 2001 |
T-cells produce acidic niches in lymph nodes to suppress their own effector functions H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ... Nature communications 11 (1), 4113, 2020 | 130 | 2020 |
Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP YK Reshetnyak, L Yao, S Zheng, S Kuznetsov, DM Engelman, ... Molecular imaging and biology 13, 1146-1156, 2011 | 125 | 2011 |
Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors LC Wyatt, A Moshnikova, T Crawford, DM Engelman, OA Andreev, ... Proceedings of the National Academy of Sciences 115 (12), E2811-E2818, 2018 | 119 | 2018 |
Applications of pHLIP technology for cancer imaging and therapy LC Wyatt, JS Lewis, OA Andreev, YK Reshetnyak, DM Engelman Trends in Biotechnology 35 (7), 653-664, 2017 | 119 | 2017 |
Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response M Sahraei, B Chaube, Y Liu, J Sun, A Kaplan, NL Price, W Ding, ... The Journal of clinical investigation 129 (12), 5518-5536, 2019 | 115 | 2019 |