Kento Onishi
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Functional immobilization of signaling proteins enables control of stem cell fate
K Alberti, RE Davey, K Onishi, S George, K Salchert, FP Seib, ...
Nature methods 5 (7), 645, 2008
2152008
LIF‐mediated control of embryonic stem cell self‐renewal emerges due to an autoregulatory loop
RE Davey, K Onishi, A Mahdavi, PW Zandstra
The FASEB Journal 21 (9), 2020-2032, 2007
872007
Manipulation of signaling thresholds in “engineered stem cell niches” identifies design criteria for pluripotent stem cell screens
R Peerani, K Onishi, A Mahdavi, E Kumacheva, PW Zandstra
PloS one 4 (7), e6438, 2009
852009
LIF signaling in stem cells and development
K Onishi, PW Zandstra
Development 142 (13), 2230-2236, 2015
782015
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells
F Moledina, G Clarke, A Oskooei, K Onishi, A Günther, PW Zandstra
Proceedings of the National Academy of Sciences 109 (9), 3264-3269, 2012
702012
Oct4 is required∼ E7. 5 for proliferation in the primitive streak
B DeVeale, I Brokhman, P Mohseni, T Babak, C Yoon, A Lin, K Onishi, ...
PLoS Genet 9 (11), e1003957, 2013
602013
Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions
A Yachie‐Kinoshita, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, ...
Molecular systems biology 14 (1), e7952, 2018
252018
Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK–STAT signaling
K Onishi, PD Tonge, A Nagy, PW Zandstra
Integrative Biology 4 (11), 1367-1376, 2012
202012
Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry
JA Hewel, J Liu, K Onishi, V Fong, S Chandran, JB Olsen, O Pogoutse, ...
Molecular & Cellular Proteomics 9 (11), 2460-2473, 2010
202010
Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency
K Onishi, PD Tonge, A Nagy, PW Zandstra
Stem cell reports 3 (1), 156-168, 2014
182014
Patterning of sharp cellular interfaces with a reconfigurable elastic substrate
A Curtis, DJ Li, B DeVeale, K Onishi, MY Kim, R Blelloch, DJ Laird, EE Hui
Integrative Biology 9 (1), 50-57, 2017
32017
Modeling signaling-dependent pluripotent cell states with boolean logic can predict cell fate transitions
A Yachie-Kinoshita, K Onishi, J Ostblom, E Posfai, J Rossant, ...
bioRxiv, 115683, 2017
22017
Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
K Onishi, NC Manley, CR Halberstadt, EM Whiteley
US Patent App. 16/750,975, 2020
2020
Dissecting the Role of the Stem Cell Niche in Driving Conversion Between Pluripotent States
K Onishi
2014
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Artículos 1–14