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Wardiya Afshar-Saber
Wardiya Afshar-Saber
Harvard Medical School - Boston Children’s Hospital
Dirección de correo verificada de childrens.harvard.edu
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Año
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts
BJ Wainger, ED Buttermore, JT Oliveira, C Mellin, S Lee, WA Saber, ...
Nature neuroscience 18 (1), 17-24, 2015
2102015
Wide-field multiphoton imaging through scattering media without correction
A Escobet-Montalbán, R Spesyvtsev, M Chen, WA Saber, M Andrews, ...
Science Advances 4 (10), eaau1338, 2018
582018
Recent advances in human stem cell-based modeling of Tuberous Sclerosis Complex
W Afshar Saber, M Sahin
Molecular Autism 11 (1), 16, 2020
302020
Balancing serendipity and reproducibility: Pluripotent stem cells as experimental systems for intellectual and developmental disorders
NC Anderson, PF Chen, K Meganathan, WA Saber, AJ Petersen, ...
Stem cell reports 16 (6), 1446-1457, 2021
252021
All-optical assay to study biological neural networks
W Afshar Saber, FM Gasparoli, MG Dirks, FJ Gunn-Moore, M Antkowiak
Frontiers in neuroscience 12, 451, 2018
232018
AP-4-mediated axonal transport controls endocannabinoid production in neurons
AK Davies, JE Alecu, M Ziegler, CG Vasilopoulou, F Merciai, H Jumo, ...
Nature Communications 13 (1), 1058, 2022
182022
Cross-IDDRC Human Stem Cell Working Group Balancing serendipity and reproducibility: pluripotent stem cells as experimental systems for intellectual and developmental disorders
NC Anderson, PF Chen, K Meganathan, WA Saber, AJ Petersen, ...
Stem Cell Rep 16, 1446-1457, 2021
62021
Generation and characterization of six human induced pluripotent stem cell lines (iPSC) from three families with AP4M1-associated hereditary spastic paraplegia (SPG50)
K Eberhardt, H Jumo, A D'Amore, JE Alecu, M Ziegler, WA Saber, M Sahin, ...
Stem cell research 53, 102335, 2021
32021
AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB
AK Davies, M Ziegler, H Jumo, WA Saber, D Ebrahimi-Fakhari, ...
BiorXiv, 2020.10. 25.353995, 2020
32020
ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations
W Afshar-Saber, NA Teaney, KD Winden, H Jumo, X Shi, G McGinty, ...
Neurobiology of disease 190, 106386, 2024
22024
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder
I Tokatly Latzer, JB Roullet, W Afshar-Saber, HHC Lee, M Bertoldi, ...
Journal of Neurodevelopmental Disorders 16 (1), 21, 2024
12024
High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia
A Saffari, B Brechmann, C Böger, WA Saber, H Jumo, D Whye, D Wood, ...
Nature Communications 15 (1), 584, 2024
12024
A robust pipeline for the multi‐stage accelerated differentiation of functional 3D cortical organoids from human pluripotent stem cells
D Whye, D Wood, WA Saber, EM Norabuena, NR Makhortova, M Sahin, ...
Current protocols 3 (1), e641, 2023
12023
AP-4-mediated axonal transport controls endocannabinoid production in neurons-Image analysis pipelines
AK Davies, JE Alecu, M Ziegler, CG Vasilopoulou, F Merciai, H Jumo, ...
Zenodo, 2021
12021
TRAFIX: Imaging at depth with temporal focusing and single-pixel detection
A Escobet-Montalbán, M Chen, P Wijesinghe, K Dholakia
Novel Techniques in Microscopy, NT1C. 4, 2019
12019
Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls
W Afshar-Saber, C Chen, NA Teaney, K Kim, Z Yang, FM Gasparoli, ...
Stem Cell Research, 103424, 2024
2024
In vitro and in vivo models for neurodevelopmental disorders
A D'Amore, M Marchese, W Afshar-Saber, MQ Hameed
Frontiers in Neuroscience 17, 1239577, 2023
2023
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia
A Saffari, B Brechmann, C Boeger, WA Saber, D Whye, D Wood, ...
Research Square, 2023
2023
The Contribution of Rapamycin-Insensitive Processes to Neurological Symptoms in TSC
M Sahin
2022
Deep tissue, wide-field multiphoton imaging using TEMPPIX
A Escobet-Montalbán, R Spesyvtsev, M Chen, WA Saber, M Andrews, ...
CLEO: Applications and Technology, AF2M. 3, 2018
2018
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