Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10723 | 2021 |
Biologically active sphingolipids in cancer pathogenesis and treatment B Ogretmen, YA Hannun Nature Reviews Cancer 4 (8), 604-616, 2004 | 1502 | 2004 |
Sphingolipid metabolism in cancer signalling and therapy B Ogretmen Nature Reviews Cancer 18 (1), 33-50, 2018 | 904 | 2018 |
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy RD Sentelle, CE Senkal, W Jiang, S Ponnusamy, S Gencer, SP Selvam, ... Nature Chemical Biology 8 (10), 831-838, 2012 | 528 | 2012 |
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells CE Chalfant, K Rathman, RL Pinkerman, RE Wood, LM Obeid, ... Journal of Biological Chemistry 277 (15), 12587-12595, 2002 | 409 | 2002 |
Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance S Ponnusamy, M Meyers-Needham, CE Senkal, SA Saddoughi, ... Future oncology 6 (10), 1603-1624, 2010 | 359 | 2010 |
Roles of bioactive sphingolipids in cancer biology and therapeutics SA Saddoughi, P Song, B Ogretmen Lipids in Health and Disease, 413-440, 2008 | 307 | 2008 |
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ... EMBO molecular medicine 5 (1), 105-121, 2013 | 292 | 2013 |
Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways CE Senkal, S Ponnusamy, J Bielawski, YA Hannun, B Ogretmen The FASEB Journal 24 (1), 296, 2010 | 271 | 2010 |
Defects in cell growth regulation by C18: 0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas S Koybasi, CE Senkal, K Sundararaj, S Spassieva, J Bielawski, W Osta, ... Journal of Biological Chemistry 279 (43), 44311-44319, 2004 | 268 | 2004 |
Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells Y Baran, A Salas, CE Senkal, U Gunduz, J Bielawski, LM Obeid, ... Journal of Biological Chemistry 282 (15), 10922-10934, 2007 | 267 | 2007 |
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ... The Journal of clinical investigation 123 (10), 4144-4157, 2013 | 259 | 2013 |
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling A Mukhopadhyay, SA Saddoughi, P Song, I Sultan, S Ponnusamy, ... The FASEB Journal 23 (3), 751, 2009 | 248 | 2009 |
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line B Ogretmen, BJ Pettus, MJ Rossi, R Wood, J Usta, Z Szulc, A Bielawska, ... Journal of Biological Chemistry 277 (15), 12960-12969, 2002 | 246 | 2002 |
Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue KR Johnson, KY Johnson, HG Crellin, B Ogretmen, AM Boylan, RA Harley, ... Journal of Histochemistry & Cytochemistry 53 (9), 1159-1166, 2005 | 244 | 2005 |
CD38-NAD+ axis regulates immunotherapeutic anti-tumor T cell response S Chatterjee, A Daenthanasanmak, P Chakraborty, MW Wyatt, P Dhar, ... Cell metabolism 27 (1), 85-100. e8, 2018 | 227 | 2018 |
Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): Attenuation of C18-ceramide in HNSCC tumors correlates … S Karahatay, K Thomas, S Koybasi, CE Senkal, S ElOjeimy, X Liu, ... Cancer letters 256 (1), 101-111, 2007 | 222 | 2007 |
Diverse functions of ceramide in cancer cell death and proliferation SA Saddoughi, B Ogretmen Advances in cancer research 117, 37-58, 2013 | 214 | 2013 |
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas CE Senkal, S Ponnusamy, MJ Rossi, J Bialewski, D Sinha, JC Jiang, ... Molecular cancer therapeutics 6 (2), 712-722, 2007 | 197 | 2007 |
FAS activation induces dephosphorylation of SR proteins CE Chalfant, B Ogretmen, S Galadari, BJ Kroesen, BJ Pettus, YA Hannun Journal of Biological Chemistry 276 (48), 44848-44855, 2001 | 197 | 2001 |