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Besim Ogretmen
Besim Ogretmen
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107232021
Biologically active sphingolipids in cancer pathogenesis and treatment
B Ogretmen, YA Hannun
Nature Reviews Cancer 4 (8), 604-616, 2004
15022004
Sphingolipid metabolism in cancer signalling and therapy
B Ogretmen
Nature Reviews Cancer 18 (1), 33-50, 2018
9042018
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
RD Sentelle, CE Senkal, W Jiang, S Ponnusamy, S Gencer, SP Selvam, ...
Nature Chemical Biology 8 (10), 831-838, 2012
5282012
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells
CE Chalfant, K Rathman, RL Pinkerman, RE Wood, LM Obeid, ...
Journal of Biological Chemistry 277 (15), 12587-12595, 2002
4092002
Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
S Ponnusamy, M Meyers-Needham, CE Senkal, SA Saddoughi, ...
Future oncology 6 (10), 1603-1624, 2010
3592010
Roles of bioactive sphingolipids in cancer biology and therapeutics
SA Saddoughi, P Song, B Ogretmen
Lipids in Health and Disease, 413-440, 2008
3072008
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ...
EMBO molecular medicine 5 (1), 105-121, 2013
2922013
Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways
CE Senkal, S Ponnusamy, J Bielawski, YA Hannun, B Ogretmen
The FASEB Journal 24 (1), 296, 2010
2712010
Defects in cell growth regulation by C18: 0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas
S Koybasi, CE Senkal, K Sundararaj, S Spassieva, J Bielawski, W Osta, ...
Journal of Biological Chemistry 279 (43), 44311-44319, 2004
2682004
Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells
Y Baran, A Salas, CE Senkal, U Gunduz, J Bielawski, LM Obeid, ...
Journal of Biological Chemistry 282 (15), 10922-10934, 2007
2672007
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ...
The Journal of clinical investigation 123 (10), 4144-4157, 2013
2592013
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
A Mukhopadhyay, SA Saddoughi, P Song, I Sultan, S Ponnusamy, ...
The FASEB Journal 23 (3), 751, 2009
2482009
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line
B Ogretmen, BJ Pettus, MJ Rossi, R Wood, J Usta, Z Szulc, A Bielawska, ...
Journal of Biological Chemistry 277 (15), 12960-12969, 2002
2462002
Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue
KR Johnson, KY Johnson, HG Crellin, B Ogretmen, AM Boylan, RA Harley, ...
Journal of Histochemistry & Cytochemistry 53 (9), 1159-1166, 2005
2442005
CD38-NAD+ axis regulates immunotherapeutic anti-tumor T cell response
S Chatterjee, A Daenthanasanmak, P Chakraborty, MW Wyatt, P Dhar, ...
Cell metabolism 27 (1), 85-100. e8, 2018
2272018
Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): Attenuation of C18-ceramide in HNSCC tumors correlates …
S Karahatay, K Thomas, S Koybasi, CE Senkal, S ElOjeimy, X Liu, ...
Cancer letters 256 (1), 101-111, 2007
2222007
Diverse functions of ceramide in cancer cell death and proliferation
SA Saddoughi, B Ogretmen
Advances in cancer research 117, 37-58, 2013
2142013
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas
CE Senkal, S Ponnusamy, MJ Rossi, J Bialewski, D Sinha, JC Jiang, ...
Molecular cancer therapeutics 6 (2), 712-722, 2007
1972007
FAS activation induces dephosphorylation of SR proteins
CE Chalfant, B Ogretmen, S Galadari, BJ Kroesen, BJ Pettus, YA Hannun
Journal of Biological Chemistry 276 (48), 44848-44855, 2001
1972001
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