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Jahir M. Gutierrez
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Year
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12, 1-7, 2016
3092016
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell systems 3 (5), 434-443. e8, 2016
2412016
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide
S Isabel, L Graña-Miraglia, JM Gutierrez, C Bundalovic-Torma, HE Groves, ...
Scientific reports 10 (1), 14031, 2020
2272020
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature communications 11 (1), 68, 2020
1072020
The emerging role of systems biology for engineering protein production in CHO cells
CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis
Current Opinion in Biotechnology 51, 64-69, 2018
1052018
Multiplex secretome engineering enhances recombinant protein production and purity
S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ...
Nature communications 11 (1), 1908, 2020
902020
Optimizing eukaryotic cell hosts for protein production through systems biotechnology and genome‐scale modeling
JM Gutierrez, NE Lewis
Biotechnology journal 10 (7), 939-949, 2015
592015
Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
512016
Cardiovascular events associated with chimeric antigen receptor T cell therapy: cross-sectional FDA adverse events reporting system analysis
A Guha, D Addison, P Jain, JM Gutierrez, A Ghosh, C Roddie, M de Lima, ...
Biology of Blood and Marrow Transplantation 26 (12), 2211-2216, 2020
492020
Antibody optimization enabled by artificial intelligence predictions of binding affinity and naturalness
S Bachas, G Rakocevic, D Spencer, AV Sastry, R Haile, JM Sutton, ...
BioRxiv, 2022.08. 16.504181, 2022
312022
Model-based assessment of mammalian cell metabolic functionalities using omics data
A Richelle, BP Kellman, AT Wenzel, AWT Chiang, T Reagan, ...
Cell reports methods 1 (3), 2021
30*2021
Cardiovascular adverse events are associated with usage of immune checkpoint inhibitors in real-world clinical data across the United States
P Jain, JG Bugarin, A Guha, C Jain, N Patil, T Shen, I Stanevich, V Nikore, ...
ESMO Open 6 (5), 2021
302021
Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3
JC Granados, A Richelle, JM Gutierrez, P Zhang, X Zhang, V Bhatnagar, ...
Journal of Biological Chemistry 296, 2021
262021
Unlocking de novo antibody design with generative artificial intelligence
A Shanehsazzadeh, S Bachas, M McPartlon, G Kasun, JM Sutton, ...
bioRxiv, 2023.01. 08.523187, 2023
192023
Cardiovascular adverse events associated with BRAF versus BRAF/MEK inhibitor: Cross‐sectional and longitudinal analysis using two large national registries
A Guha, P Jain, MG Fradley, D Lenihan, JM Gutierrez, C Jain, M de Lima, ...
Cancer medicine 10 (12), 3862-3872, 2021
182021
Combating viral contaminants in CHO cells by engineering innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 8827, 2019
162019
The human secretome–the proteins secreted from human cells
M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ...
BioRxiv, 465815, 2018
162018
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide. Sci Rep 10: 14031
S Isabel, L Graña-Miraglia, JM Gutierrez, C Bundalovic-Torma, HE Groves, ...
122020
Deep learning-based codon optimization with large-scale synonymous variant datasets enables generalized tunable protein expression
DA Constant, JM Gutierrez, AV Sastry, R Viazzo, NR Smith, J Hossain, ...
bioRxiv, 2023.02. 11.528149, 2023
82023
Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees
JM Gutierrez, M Volkovs, T Poutanen, T Watson, LC Rosella
Canadian Medical Association Open Access Journal 9 (4), E1223-E1231, 2021
62021
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Articles 1–20