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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
DS Howland, J Liu, Y She, B Goad, NJ Maragakis, B Kim, J Erickson, ...
Proceedings of the National Academy of Sciences 99 (3), 1604-1609, 2002
10612002
Mechanisms of disease: astrocytes in neurodegenerative disease
NJ Maragakis, JD Rothstein
Nature clinical practice Neurology 2 (12), 679-689, 2006
10522006
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ...
Neuron 80 (2), 415-428, 2013
10102013
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ...
Nature 507 (7491), 195-200, 2014
10012014
Protective role of reactive astrocytes in brain ischemia
L Li, A Lundkvist, D Andersson, U Wilhelmsson, N Nagai, AC Pardo, ...
Journal of Cerebral Blood Flow & Metabolism 28 (3), 468-481, 2008
6142008
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
5792018
Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease
AC Lepore, B Rauck, C Dejea, AC Pardo, MS Rao, JD Rothstein, ...
Nature neuroscience 11 (11), 1294-1301, 2008
4892008
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
4392020
Glutamate transporters: animal models to neurologic disease
NJ Maragakis, JD Rothstein
Neurobiology of disease 15 (3), 461-473, 2004
4392004
Glutamate transporters in neurologic disease
NJ Maragakis, JD Rothstein
Archives of neurology 58 (3), 365-370, 2001
4042001
Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury
DA Kerr, J Lladó, MJ Shamblott, NJ Maragakis, DN Irani, TO Crawford, ...
Journal of Neuroscience 23 (12), 5131-5140, 2003
3682003
Recovery from paralysis in adult rats using embryonic stem cells
DM Deshpande, YS Kim, T Martinez, J Carmen, S Dike, I Shats, LL Rubin, ...
Annals of neurology 60 (1), 32-44, 2006
3402006
Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors
J Lladó, C Haenggeli, NJ Maragakis, EY Snyder, JD Rothstein
Molecular and Cellular Neuroscience 27 (3), 322-331, 2004
2872004
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
ST Papadeas, SE Kraig, C O'Banion, AC Lepore, NJ Maragakis
Proceedings of the National Academy of Sciences 108 (43), 17803-17808, 2011
2552011
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking
FM Laird, MH Farah, S Ackerley, A Hoke, N Maragakis, JD Rothstein, ...
Journal of Neuroscience 28 (9), 1997-2005, 2008
2362008
Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons
RP Irwin, NJ Maragakis, MA Rogawski, RH Purdy, DH Farb, SM Paul
Neuroscience letters 141 (1), 30-34, 1992
2121992
Mechanisms, models and biomarkers in amyotrophic lateral sclerosis
MR Turner, R Bowser, L Bruijn, L Dupuis, A Ludolph, M McGrath, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (sup1), 19-32, 2013
2062013
A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus
T Ueki, M Tanaka, K Yamashita, S Mikawa, ZF Qiu, NJ Maragakis, ...
Journal of Neuroscience 23 (37), 11732-11740, 2003
1762003
Altered expression of the glutamate transporter EAAT2b in neurological disease
NJ Maragakis, M Dykes‐Hoberg, JD Rothstein
Annals of neurology 55 (4), 469-477, 2004
1682004
Concordant but varied phenotypes among Duchenne muscular dystrophy patient-specific myoblasts derived using a human iPSC-based model
IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ...
Cell reports 15 (10), 2301-2312, 2016
1642016
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