Tumor mutational load predicts survival after immunotherapy across multiple cancer types RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ... Nature genetics 51 (2), 202-206, 2019 | 3096 | 2019 |
A comparative encyclopedia of DNA elements in the mouse genome F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, ... Nature 515 (7527), 355-364, 2014 | 1907 | 2014 |
Immunology of COVID-19: current state of the science N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunity 52 (6), 910-941, 2020 | 1701 | 2020 |
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner A Chaudhry, D Rudra, P Treuting, RM Samstein, Y Liang, A Kas, ... Science 326 (5955), 986-991, 2009 | 1189 | 2009 |
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation A Chaudhry, RM Samstein, P Treuting, Y Liang, MC Pils, JM Heinrich, ... Immunity 34 (4), 566-578, 2011 | 1061 | 2011 |
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy D Chowell, LGT Morris, CM Grigg, JK Weber, RM Samstein, V Makarov, ... Science 359 (6375), 582-587, 2018 | 1001 | 2018 |
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells O Kollet, A Dar, S Shivtiel, A Kalinkovich, K Lapid, Y Sztainberg, M Tesio, ... Nature medicine 12 (6), 657-664, 2006 | 919 | 2006 |
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict RM Samstein, SZ Josefowicz, A Arvey, PM Treuting, AY Rudensky Cell 150 (1), 29-38, 2012 | 682 | 2012 |
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification RM Samstein, A Arvey, SZ Josefowicz, X Peng, A Reynolds, R Sandstrom, ... Cell 151 (1), 153-166, 2012 | 502 | 2012 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network D Rudra, P Deroos, A Chaudhry, RE Niec, A Arvey, RM Samstein, ... Nature immunology 13 (10), 1010-1019, 2012 | 482 | 2012 |
Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response R Mandal, RM Samstein, KW Lee, JJ Havel, H Wang, C Krishna, ... Science 364 (6439), 485-491, 2019 | 444 | 2019 |
Immunogenic neoantigens derived from gene fusions stimulate T cell responses W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, ... Nature medicine 25 (5), 767-775, 2019 | 310 | 2019 |
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution J Vierstra, E Rynes, R Sandstrom, M Zhang, T Canfield, RS Hansen, ... Science 346 (6212), 1007-1012, 2014 | 277 | 2014 |
Sinai Immunology Review Project. Immunology of COVID-19: current state of the science N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunity 52 (6), 910-941, 2020 | 267 | 2020 |
Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting TM Fahmy, RM Samstein, CC Harness, WM Saltzman Biomaterials 26 (28), 5727-5736, 2005 | 231 | 2005 |
Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells A Arvey, J Van Der Veeken, RM Samstein, Y Feng, ... Nature immunology 15 (6), 580-587, 2014 | 228 | 2014 |
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification AM Leader, JA Grout, BB Maier, BY Nabet, MD Park, A Tabachnikova, ... Cancer cell 39 (12), 1594-1609. e12, 2021 | 183 | 2021 |
The association between tumor mutational burden and prognosis is dependent on treatment context C Valero, M Lee, D Hoen, J Wang, Z Nadeem, N Patel, MA Postow, ... Nature genetics 53 (1), 11-15, 2021 | 162 | 2021 |
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types D Chowell, SK Yoo, C Valero, A Pastore, C Krishna, M Lee, D Hoen, ... Nature biotechnology 40 (4), 499-506, 2022 | 146 | 2022 |
Shared immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors V Roudko, CC Bozkus, T Orfanelli, CB McClain, C Carr, T O’Donnell, ... Cell 183 (6), 1634-1649. e17, 2020 | 140 | 2020 |