| Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ... Nature Biotechnology, 1, 2019 | 524 | 2019 |
| CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity BD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ... Nature biotechnology, 1, 2019 | 409 | 2019 |
| CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma BD Choi, X Yu, AP Castano, H Darr, DB Henderson, AA Bouffard, ... Journal for ImmunoTherapy of Cancer 7 (1), 1-8, 2019 | 243 | 2019 |
| Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment I Scarfò, MV Maus Journal for immunotherapy of cancer 5 (1), 28, 2017 | 195 | 2017 |
| CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours RC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ... Nature 604 (7906), 563-570, 2022 | 185 | 2022 |
| Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomide M Jan, I Scarfò, RC Larson, A Walker, A Schmidts, AA Guirguis, JA Gasser, ... Science Translational Medicine 13 (575), 2021 | 160 | 2021 |
| Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response PA Baeuerle, J Ding, E Patel, N Thorausch, H Horton, J Gierut, I Scarfo, ... Nature Communications 10 (1), 2087, 2019 | 133 | 2019 |
| Anti-CD37 chimeric antigen receptor T cells are active against B and T cell lymphomas I Scarfò, M Ormhøj, MJ Frigault, AP Castano, S Lorrey, AA Bouffard, ... Blood, blood-2018-04-842708, 2018 | 120 | 2018 |
| Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts I Scarfò, E Pellegrino, E Mereu, I Kwee, L Agnelli, E Bergaggio, G Garaffo, ... Blood 127 (2), 221-232, 2016 | 114 | 2016 |
| The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma R Piva, S Deaglio, R Fama, R Buonincontri, I Scarfo, A Bruscaggin, ... Leukemia 29 (2), 503-507, 2015 | 110 | 2015 |
| Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma A Schmidts, M Ormhøj, BD Choi, AO Taylor, AA Bouffard, I Scarfò, ... Blood advances 3 (21), 3248-3260, 2019 | 91 | 2019 |
| Chimeric antigen receptor T cells targeting CD79b show efficacy in lymphoma with or without co-targeting CD19 M Ormhøj, I Scarfò, ML Cabral, SR Bailey, SJ Lorrey, AA Bouffard, ... Clinical Cancer Research, clincanres. 1337.2019, 2019 | 70 | 2019 |
| Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ... Cancer Cell 40 (5), 494-508. e5, 2022 | 64 | 2022 |
| The RNA-binding protein ESRP1 promotes human colorectal cancer progression S Fagoonee, G Picco, F Orso, A Arrigoni, DL Longo, M Forni, I Scarfò, ... Oncotarget 8 (6), 10007, 2017 | 64 | 2017 |
| The heterogeneous landscape of ALK negative ALCL E Mereu, E Pellegrino, I Scarfò, G Inghirami, R Piva Oncotarget 8 (11), 18525, 2017 | 35 | 2017 |
| CAR-based approaches to Cutaneous T-cell lymphoma I Scarfo, MJ Frigault, MV Maus Frontiers in Oncology 9, 2019 | 22 | 2019 |
| Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources A Schmidts, LC Marsh, AA Srivastava, AA Bouffard, AC Boroughs, I Scarfò, ... Journal for immunotherapy of cancer 8 (2), 2020 | 20 | 2020 |
| Dynamic Profiling of Antitumor Activity of CAR T Cells Using Micropatterned Tumor Arrays X Wang, I Scarfò, A Schmidts, M Toner, MV Maus, D Irimia Advanced Science, 1901829, 2019 | 20 | 2019 |
| Single-cell imaging of T cell immunotherapy responses in vivo C Yan, Q Yang, S Zhang, DG Millar, EJ Alpert, D Do, A Veloso, ... Journal of Experimental Medicine 218 (10), e20210314, 2021 | 17 | 2021 |
| Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells I Scarfò, MV Maus Cancer Cell 37 (2), 143-144, 2020 | 6 | 2020 |
