A Planning Strategy for Diversity-Oriented Synthesis MD Burke, SL Schreiber Angewandte Chemie - International Edition 43 (1), 46-58, 2004 | 1827 | 2004 |
Amphotericin primarily kills yeast by simply binding ergosterol KC Gray, DS Palacios, I Dailey, MM Endo, BE Uno, BC Wilcock, MD Burke Proceedings of the National Academy of Sciences 109 (7), 2234-2239, 2012 | 725 | 2012 |
A general solution for unstable boronic acids: slow-release cross-coupling from air-stable MIDA boronates DM Knapp, EP Gillis, MD Burke Journal of the American Chemical Society 131 (20), 6961-6963, 2009 | 694 | 2009 |
A simple and modular strategy for small molecule synthesis: iterative Suzuki− Miyaura coupling of B-protected haloboronic acid building blocks EP Gillis, MD Burke Journal of the American Chemical Society 129 (21), 6716-6717, 2007 | 597 | 2007 |
Synthesis of many different types of organic small molecules using one automated process J Li, SG Ballmer, EP Gillis, S Fujii, MJ Schmidt, AME Palazzolo, ... Science 347 (6227), 1221-1226, 2015 | 573 | 2015 |
Amphotericin forms an extramembranous and fungicidal sterol sponge TM Anderson, MC Clay, AG Cioffi, KA Diaz, GS Hisao, MD Tuttle, ... Nature chemical biology 10 (5), 400-406, 2014 | 538 | 2014 |
Generating diverse skeletons of small molecules combinatorially MD Burke, EM Berger, SL Schreiber Science 302 (5645), 613-618, 2003 | 462 | 2003 |
Simple, efficient, and modular syntheses of polyene natural products via iterative cross-coupling SJ Lee, KC Gray, JS Paek, MD Burke Journal of the American Chemical Society 130 (2), 466-468, 2008 | 346 | 2008 |
Multistep synthesis of complex boronic acids from simple MIDA boronates EP Gillis, MD Burke Journal of the American Chemical Society 130 (43), 14084-14085, 2008 | 289 | 2008 |
A general solution for the 2-pyridyl problem GR Dick, EM Woerly, MD Burke Angewandte Chemie (International ed. in English) 51 (11), 2667, 2012 | 254 | 2012 |
Iterative cross-couplng with MIDA boronates: towards a general platform for small molecule synthesis EP Gillis, MD Burke Aldrichimica acta 42 (1), 17, 2009 | 252 | 2009 |
Eine Strategie für die Diversitäts‐orientierte Synthese MD Burke, SL Schreiber Angewandte Chemie 116 (1), 48-60, 2004 | 250 | 2004 |
Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction EM Woerly, J Roy, MD Burke Nature chemistry 6 (6), 484-491, 2014 | 225 | 2014 |
A synthesis strategy yielding skeletally diverse small molecules combinatorially MD Burke, EM Berger, SL Schreiber Journal of the American Chemical Society 126 (43), 14095-14104, 2004 | 221 | 2004 |
The Molecular Industrial Revolution: Automated Synthesis of Small Molecules M Trobe, MD Burke Angewandte Chemie International Edition 57 (16), 4192-4214, 2018 | 194 | 2018 |
From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks J Li, AS Grillo, MD Burke Accounts of chemical research 48 (8), 2297-2307, 2015 | 191 | 2015 |
Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities DS Palacios, I Dailey, DM Siebert, BC Wilcock, MD Burke Proceedings of the National Academy of Sciences 108 (17), 6733-6738, 2011 | 191 | 2011 |
Pinene-Derived Iminodiacetic Acid (PIDA): A Powerful Ligand for Stereoselective Synthesis and Iterative Cross-Coupling of C(sp3) Boronate Building Blocks J Li, MD Burke Journal of the American Chemical Society 133 (35), 13774-13777, 2011 | 178 | 2011 |
Vinyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis BE Uno, EP Gillis, MD Burke Tetrahedron 65 (16), 3130-3138, 2009 | 171 | 2009 |
Stereoretentive Suzuki− Miyaura Coupling of Haloallenes Enables Fully Stereocontrolled Access to (−)-Peridinin EM Woerly, AH Cherney, EK Davis, MD Burke Journal of the American Chemical Society 132 (20), 6941-6943, 2010 | 160 | 2010 |