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Peter J. Shepard
Peter J. Shepard
Design Therapeutics
Dirección de correo verificada de designtx.com
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The SR protein family
PJ Shepard, KJ Hertel
Genome biology 10, 1-9, 2009
5312009
Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq
PJ Shepard, EA Choi, J Lu, LA Flanagan, KJ Hertel, Y Shi
Rna 17 (4), 761-772, 2011
4692011
Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers
C DeBoever, EM Ghia, PJ Shepard, L Rassenti, CL Barrett, K Jepsen, ...
PLoS computational biology 11 (3), e1004105, 2015
2272015
Conserved RNA secondary structures promote alternative splicing
PJ Shepard, KJ Hertel
Rna 14 (8), 1463-1469, 2008
1882008
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling
JM Yeakley, PJ Shepard, DE Goyena, HC VanSteenhouse, JD McComb, ...
PloS one 12 (5), e0178302, 2017
1732017
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
FA Grimm, Y Iwata, O Sirenko, GA Chappell, FA Wright, DM Reif, ...
Green chemistry 18 (16), 4407-4419, 2016
872016
Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development
E Koller, S Propp, H Zhang, C Zhao, X Xiao, MY Chang, SA Hirsch, ...
Cancer research 66 (4), 2059-2066, 2006
592006
Competing upstream 5′ splice sites enhance the rate of proximal splicing
MJ Hicks, WF Mueller, PJ Shepard, KJ Hertel
Molecular and cellular biology, 2010
532010
Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq
A Limonciel, G Ates, G Carta, A Wilmes, M Watzele, PJ Shepard, ...
Archives of toxicology 92, 2517-2531, 2018
522018
Profiling expression at transcriptome scale
PJ Shepard, JM Yeakley, B Seligmann
US Patent 9,938,566, 2018
512018
Efficient internal exon recognition depends on near equal contributions from the 3′ and 5′ splice sites
PJ Shepard, EA Choi, A Busch, KJ Hertel
Nucleic acids research 39 (20), 8928-8937, 2011
472011
Aberrant DNA methylation in human iPSCs associates with MYC-binding motifs in a clone-specific manner independent of genetics
AD Panopoulos, EN Smith, AD Arias, PJ Shepard, Y Hishida, V Modesto, ...
Cell Stem Cell 20 (4), 505-517. e6, 2017
422017
Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development
EN Smith, EM Ghia, CM DeBoever, LZ Rassenti, K Jepsen, KA Yoon, ...
Blood cancer journal 5 (4), e303-e303, 2015
382015
Extraction-free whole transcriptome gene expression analysis of FFPE sections and histology-directed subareas of tissue
CL Trejo, M Babić, E Imler, M Gonzalez, SI Bibikov, PJ Shepard, ...
PLoS One 14 (2), e0212031, 2019
322019
Jagged 2 inhibitors for inducing apoptosis
E Koller, P Shepard
US Patent App. 10/096,399, 2003
282003
Consanguinity and rare mutations outside of MCCC genes underlie nonspecific phenotypes of MCCD
PJ Shepard, BA Barshop, MR Baumgartner, JB Hansen, K Jepsen, ...
Genetics in medicine 17 (8), 660-667, 2015
142015
Genetic ancestry of participants in the National Children’s Study
EN Smith, K Jepsen, AD Arias, PJ Shepard, CD Chambers, KA Frazer
Genome biology 15, 1-7, 2014
142014
Embracing the complexity of pre-mRNA splicing
PJ Shepard, KJ Hertel
Cell research 20 (8), 866-868, 2010
72010
Development of a zebrafish s1500+ sentinel gene set for high-throughput transcriptomics
MR Balik-Meisner, D Mav, DP Phadke, LJ Everett, RR Shah, T Tal, ...
Zebrafish 16 (4), 331-347, 2019
52019
Targeted whole transcriptome gene expression profiling for mechanistic toxicology
H VanSteenhouse, P Shepard, J Yeakley, B Seligmann
Toxicol. Lett 280, S295, 2017
22017
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Artículos 1–20