| Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment PA Yushkevich, JB Pluta, H Wang, L Xie, SL Ding, EC Gertje, L Mancuso, ... Human brain mapping 36 (1), 258-287, 2015 | 634 | 2015 |
| Effects of the insulin sensitizer metformin in Alzheimer disease: pilot data from a randomized placebo-controlled crossover study AM Koenig, D Mechanic-Hamilton, SX Xie, MF Combs, AR Cappola, L Xie, ... Alzheimer Disease & Associated Disorders 31 (2), 107-113, 2017 | 338 | 2017 |
| Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology DH Adler, LEM Wisse, R Ittyerah, JB Pluta, SL Ding, L Xie, J Wang, ... Proceedings of the National Academy of Sciences 115 (16), 4252-4257, 2018 | 186 | 2018 |
| Early stages of tau pathology and its associations with functional connectivity, atrophy and memory D Berron, JW Vogel, PS Insel, JB Pereira, L Xie, LEM Wisse, ... Brain 144 (9), 2771-2783, 2021 | 155 | 2021 |
| A protocol for manual segmentation of medial temporal lobe subregions in 7 Tesla MRI D Berron, P Vieweg, A Hochkeppler, JB Pluta, SL Ding, A Maass, A Luther, ... NeuroImage: Clinical 15, 466-482, 2017 | 154 | 2017 |
| Artificial intelligence system approaching neuroradiologist-level differential diagnosis accuracy at brain MRI AM Rauschecker, JD Rudie, L Xie, J Wang, MT Duong, EJ Botzolakis, ... Radiology 295 (3), 626-637, 2020 | 143 | 2020 |
| Automated segmentation of medial temporal lobe subregions on in vivo T1‐weighted MRI in early stages of Alzheimer's disease L Xie, LEM Wisse, J Pluta, R de Flores, V Piskin, JV Manjón, H Wang, ... Human brain mapping 40 (12), 3431-3451, 2019 | 98 | 2019 |
| Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease R de Flores, LEM Wisse, SR Das, L Xie, CT McMillan, JQ Trojanowski, ... Alzheimer's & Dementia 16 (6), 843-852, 2020 | 81 | 2020 |
| Convolutional neural network for automated FLAIR lesion segmentation on clinical brain MR imaging MT Duong, JD Rudie, J Wang, L Xie, S Mohan, JC Gee, AM Rauschecker American Journal of Neuroradiology 40 (8), 1282-1290, 2019 | 81 | 2019 |
| Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake SR Das, L Xie, LEM Wisse, R Ittyerah, NJ Tustison, BC Dickerson, ... Neurobiology of aging 66, 49-58, 2018 | 80 | 2018 |
| Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe PA Yushkevich, M Muñoz López, MM Iñiguez de Onzoño Martin, ... Brain 144 (9), 2784-2797, 2021 | 60 | 2021 |
| Longitudinal atrophy in early Braak regions in preclinical Alzheimer's disease L Xie, LEM Wisse, SR Das, N Vergnet, M Dong, R Ittyerah, R De Flores, ... Human brain mapping 41 (16), 4704-4717, 2020 | 59 | 2020 |
| Medial temporal lobe networks in Alzheimer's disease: structural and molecular vulnerabilities R de Flores, SR Das, L Xie, LEM Wisse, X Lyu, P Shah, PA Yushkevich, ... Journal of Neuroscience 42 (10), 2131-2141, 2022 | 54 | 2022 |
| Characterization of hippocampal subfields using ex vivo MRI and histology data: Lessons for in vivo segmentation R de Flores, D Berron, SL Ding, R Ittyerah, JB Pluta, L Xie, DH Adler, ... Hippocampus 30 (6), 545-564, 2020 | 51 | 2020 |
| Multi-template analysis of human perirhinal cortex in brain MRI: Explicitly accounting for anatomical variability L Xie, JB Pluta, SR Das, LEM Wisse, H Wang, L Mancuso, D Kliot, ... Neuroimage 144, 183-202, 2017 | 50 | 2017 |
| Deep label fusion: A generalizable hybrid multi-atlas and deep convolutional neural network for medical image segmentation L Xie, LEM Wisse, J Wang, S Ravikumar, P Khandelwal, T Glenn, ... Medical image analysis 83, 102683, 2023 | 42 | 2023 |
| Accounting for the confound of meninges in segmenting entorhinal and perirhinal cortices in T1-weighted MRI L Xie, LEM Wisse, SR Das, H Wang, DA Wolk, JV Manjón, PA Yushkevich Medical Image Computing and Computer-Assisted Intervention–MICCAI 2016: 19th …, 2016 | 42 | 2016 |
| In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals SR Das, L Xie, LEM Wisse, N Vergnet, R Ittyerah, S Cui, PA Yushkevich, ... Alzheimer's & Dementia 15 (10), 1286-1295, 2019 | 40 | 2019 |
| Early tau burden correlates with higher rate of atrophy in transentorhinal cortex L Xie, SR Das, LEM Wisse, R Ittyerah, PA Yushkevich, DA Wolk, ... Journal of Alzheimer’s Disease 62 (1), 85-92, 2018 | 35 | 2018 |
| Tau‐atrophy variability reveals phenotypic heterogeneity in Alzheimer's disease SR Das, X Lyu, MT Duong, L Xie, L McCollum, R de Flores, M DiCalogero, ... Annals of neurology 90 (5), 751-762, 2021 | 34 | 2021 |
Dave WolkProfessor of Neurology, University of PennsylvaniaVerified email at uphs.upenn.edu
