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Jeffrey M. Lotthammer
Jeffrey M. Lotthammer
DBBS Graduate Student, Washington University in St. Louis
Dirección de correo verificada de wustl.edu
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Predicting locations of cryptic pockets from single protein structures using the PocketMiner graph neural network
A Meller, M Ward, J Borowsky, M Kshirsagar, JM Lotthammer, F Oviedo, ...
Nature Communications 14 (1), 1177, 2023
552023
Direct prediction of intrinsically disordered protein conformational properties from sequence
JM Lotthammer, GM Ginell, D Griffith, R Emenecker, AS Holehouse
Nat Methods 21, 465–476, 2024
212024
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ...
Elife 12, e83602, 2023
182023
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles
LA Lee, SK Barrick, A Meller, J Walklate, JM Lotthammer, JW Tay, ...
Journal of Biological Chemistry 299 (1), 2023
122023
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels
APJ Giese, WH Weng, KS Kindt, HHV Chang, JS Montgomery, EM Ratzan, ...
eLife 12, 2023
52023
In Silico Electrophysiology of Inner-Ear Mechanotransduction Channel TMC1 Models
S Walujkar, JM Lotthammer, CR Nisler, JC Sudar, A Ballesteros, ...
bioRxiv, 2021.09. 17.460860, 2021
32021
Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies
SJ Lehman, A Meller, SO Solieva, JM Lotthammer, L Greenberg, ...
bioRxiv, 2023
22023
Structuring Inner-ear Mechanotransduction
D Choudhary, Y Narui, B Neel, S Walujkar, JM Lotthammer, JC Sudar, ...
Biophysical Journal 118 (3), 13a, 2020
12020
An easy-to-use computational tool for predicting 3D properties of disordered proteins
JM Lotthammer, AS Holehouse
Nat Methods, 2024
2024
Molecular mechanisms underlying CIB function in inner-ear mechanotransduction
WH Weng, J Montgomery, S Walujkar, JM Lotthammer, APJ Giese, ...
Biophysical Journal 121 (3), 494a, 2022
2022
Exploring the myosin active/auto-inhibited state equilibrium by Markov state modeling
JM Lotthammer, A Meller, MJ Greenberg, GR Bowman
Biophysical Journal 121 (3), 260a-261a, 2022
2022
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Artículos 1–11