A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp. MG Rotordam, E Fermo, N Becker, W Barcellini, A Brüggemann, N Fertig, ... Haematologica, 2018 | 47 | 2018 |
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 394, 114961, 2020 | 33 | 2020 |
The suitability of high throughput automated patch clamp for physiological applications A Obergrussberger, I Rinke‐Weiß, TA Goetze, M Rapedius, N Brinkwirth, ... The Journal of Physiology 600 (2), 277-297, 2022 | 23 | 2022 |
Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens V Karamatic Crew, LA Tilley, TJ Satchwell, SA AlSubhi, B Jones, ... Blood 141 (2), 135-146, 2023 | 19 | 2023 |
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1 G Parsonage, K Cuthbertson, N Endesh, N Murciano, AJ Hyman, ... British Journal of Pharmacology 180 (16), 2039-2063, 2023 | 14 | 2023 |
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model X Han, M Samieegohar, BJ Ridder, WW Wu, A Randolph, P Tran, J Sheng, ... Journal of Pharmacological and Toxicological Methods 105, 106890, 2020 | 11 | 2020 |
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: best practices for Nav1. 5 peak current in a high throughput … MG Rotordam, A Obergrussberger, N Brinkwirth, K Takasuna, N Becker, ... Journal of Pharmacological and Toxicological Methods 112, 107125, 2021 | 8 | 2021 |
Different clonal responses to cypress canker disease based on transcription of suberin-related genes and bark carbohydrates’ content R Danti, MG Rotordam, G Emiliani, A Giovannelli, A Papini, C Tani, ... Trees 32, 1707-1722, 2018 | 8 | 2018 |
There is no F in APC: using physiological fluoride-free solutions for high throughput automated patch clamp experiments M Rapedius, A Obergrussberger, ESA Humphries, S Scholz, ... Frontiers in Molecular Neuroscience 15, 982316, 2022 | 7 | 2022 |
Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis R Buks, T Dagher, MG Rotordam, D Monedero Alonso, S Cochet, ... Cells 11 (1), 49, 2021 | 6 | 2021 |
Transient receptor potential channel vanilloid type 2 in red cells of cannabis consumer D Flormann, M Qiao, N Murciano, I Giulia, A Darras, S Hof, ... American journal of hematology 97 (5), E180-E183, 2022 | 5 | 2022 |
A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation N Murciano, MG Rotordam, N Becker, MJ Ludlow, G Parsonage, A Darras, ... Journal of General Physiology 155 (12), e202213132, 2023 | 2 | 2023 |
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm”[Toxicology and Applied Pharmacology volume 394C … BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 395, 2020 | 2 | 2020 |
A Yoda1-Based Approach to Investigate Piezo1 Channels in Red Blood Cells Using Automated Patch Clamp Technology MG Rotordam, E Fermo, N Becker, W Barcellini, A Brüggemann, N Fertig, ... Blood 132, 1031, 2018 | 2 | 2018 |
Adverse effects of delta-9-tetrahydrocannabinol on sickle red blood cells A Hatem, S Esperti, N Murciano, M Qiao, MG Rotordam, N Becker, ... American journal of hematology 98 (12), E383-E386, 2023 | 1 | 2023 |
Novel small-molecule modulation of PIEZO1 investigated by conventional and automated patch-clamp JA Kinsella, G Parsonage, OV Povstyan, N Murciano, R Trowbridge, ... Biophysical Journal 122 (3), 396a, 2023 | 1 | 2023 |
Ion channels involved in pain pathways: An automated patch clamp study E Dragicevic, N Becker, M Rapedius, A Obergrussberger, T Goetze, ... Acta Physiologica 227, 2019 | 1 | 2019 |
Mechanical activation of PIEZO1 channels using high throughput electrophysiology T Strassmaier, N Murciano, MG Rotordam, N Becker, M Bettale, ... Biophysical Journal 123 (3), 261a, 2024 | | 2024 |
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells P Petkova-Kirova, N Murciano, G Iacono, J Jansen, G Simionato, M Qiao, ... International Journal of Molecular Sciences 25 (3), 1416, 2024 | | 2024 |
Mechanotransduction by Membrane Proteins: A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation N Murciano, MG Rotordam, N Becker, MJ Ludlow, G Parsonage, A Darras, ... The Journal of General Physiology 155 (12), 2023 | | 2023 |