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Maria Giustina Rotordam
Maria Giustina Rotordam
Nanion Technologies GmbH
Dirección de correo verificada de nanion.de
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Año
A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp.
MG Rotordam, E Fermo, N Becker, W Barcellini, A Brüggemann, N Fertig, ...
Haematologica, 2018
472018
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ...
Toxicology and Applied Pharmacology 394, 114961, 2020
332020
The suitability of high throughput automated patch clamp for physiological applications
A Obergrussberger, I Rinke‐Weiß, TA Goetze, M Rapedius, N Brinkwirth, ...
The Journal of Physiology 600 (2), 277-297, 2022
232022
Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens
V Karamatic Crew, LA Tilley, TJ Satchwell, SA AlSubhi, B Jones, ...
Blood 141 (2), 135-146, 2023
192023
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1
G Parsonage, K Cuthbertson, N Endesh, N Murciano, AJ Hyman, ...
British Journal of Pharmacology 180 (16), 2039-2063, 2023
142023
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model
X Han, M Samieegohar, BJ Ridder, WW Wu, A Randolph, P Tran, J Sheng, ...
Journal of Pharmacological and Toxicological Methods 105, 106890, 2020
112020
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: best practices for Nav1. 5 peak current in a high throughput …
MG Rotordam, A Obergrussberger, N Brinkwirth, K Takasuna, N Becker, ...
Journal of Pharmacological and Toxicological Methods 112, 107125, 2021
82021
Different clonal responses to cypress canker disease based on transcription of suberin-related genes and bark carbohydrates’ content
R Danti, MG Rotordam, G Emiliani, A Giovannelli, A Papini, C Tani, ...
Trees 32, 1707-1722, 2018
82018
There is no F in APC: using physiological fluoride-free solutions for high throughput automated patch clamp experiments
M Rapedius, A Obergrussberger, ESA Humphries, S Scholz, ...
Frontiers in Molecular Neuroscience 15, 982316, 2022
72022
Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis
R Buks, T Dagher, MG Rotordam, D Monedero Alonso, S Cochet, ...
Cells 11 (1), 49, 2021
62021
Transient receptor potential channel vanilloid type 2 in red cells of cannabis consumer
D Flormann, M Qiao, N Murciano, I Giulia, A Darras, S Hof, ...
American journal of hematology 97 (5), E180-E183, 2022
52022
A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation
N Murciano, MG Rotordam, N Becker, MJ Ludlow, G Parsonage, A Darras, ...
Journal of General Physiology 155 (12), e202213132, 2023
22023
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm”[Toxicology and Applied Pharmacology volume 394C …
BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ...
Toxicology and Applied Pharmacology 395, 2020
22020
A Yoda1-Based Approach to Investigate Piezo1 Channels in Red Blood Cells Using Automated Patch Clamp Technology
MG Rotordam, E Fermo, N Becker, W Barcellini, A Brüggemann, N Fertig, ...
Blood 132, 1031, 2018
22018
Adverse effects of delta-9-tetrahydrocannabinol on sickle red blood cells
A Hatem, S Esperti, N Murciano, M Qiao, MG Rotordam, N Becker, ...
American journal of hematology 98 (12), E383-E386, 2023
12023
Novel small-molecule modulation of PIEZO1 investigated by conventional and automated patch-clamp
JA Kinsella, G Parsonage, OV Povstyan, N Murciano, R Trowbridge, ...
Biophysical Journal 122 (3), 396a, 2023
12023
Ion channels involved in pain pathways: An automated patch clamp study
E Dragicevic, N Becker, M Rapedius, A Obergrussberger, T Goetze, ...
Acta Physiologica 227, 2019
12019
Mechanical activation of PIEZO1 channels using high throughput electrophysiology
T Strassmaier, N Murciano, MG Rotordam, N Becker, M Bettale, ...
Biophysical Journal 123 (3), 261a, 2024
2024
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells
P Petkova-Kirova, N Murciano, G Iacono, J Jansen, G Simionato, M Qiao, ...
International Journal of Molecular Sciences 25 (3), 1416, 2024
2024
Mechanotransduction by Membrane Proteins: A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation
N Murciano, MG Rotordam, N Becker, MJ Ludlow, G Parsonage, A Darras, ...
The Journal of General Physiology 155 (12), 2023
2023
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