| CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP EM Schwiebert, ME Egan, TH Hwang, SB Fulmer, SS Allen, GR Cutting, ... Cell 81 (7), 1063-1073, 1995 | 784 | 1995 |
| Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects ME Egan, M Pearson, SA Weiner, V Rajendran, D Rubin, ... Science 304 (5670), 600-602, 2004 | 755 | 2004 |
| CFTR is a conductance regulator as well as a chloride channel EM Schwiebert, DJ Benos, ME Egan, MJ Stutts, WB Guggino Physiological reviews 79 (1), S145-S166, 1999 | 566 | 1999 |
| Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR M Egan, T Flotte, S Afione, R Solow, PL Zeitlin, BJ Carter, WB Guggino Nature 358 (6387), 581-584, 1992 | 519 | 1992 |
| In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR. RC Rubenstein, ME Egan, PL Zeitlin The Journal of clinical investigation 100 (10), 2457-2465, 1997 | 490 | 1997 |
| Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients TS Murray, M Egan, BI Kazmierczak Current opinion in pediatrics 19 (1), 83-88, 2007 | 321 | 2007 |
| Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator−/− Mice EM Bruscia, PX Zhang, E Ferreira, C Caputo, JW Emerson, D Tuck, ... American journal of respiratory cell and molecular biology 40 (3), 295-304, 2009 | 255 | 2009 |
| Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate PL Zeitlin, M Diener-West, RC Rubenstein, MP Boyle, CKK Lee, ... Molecular Therapy 6 (1), 119-126, 2002 | 255 | 2002 |
| Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells ME Egan, J Glöckner-Pagel, CA Ambrose, PA Cahill, L Pappoe, ... Nature medicine 8 (5), 485-492, 2002 | 252 | 2002 |
| Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic … CM McNicholas, WB Guggino, EM Schwiebert, SC Hebert, G Giebisch, ... Proceedings of the National Academy of Sciences 93 (15), 8083-8088, 1996 | 248 | 1996 |
| Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin MS Cartiera, EC Ferreira, C Caputo, ME Egan, MJ Caplan, WM Saltzman Molecular pharmaceutics 7 (1), 86-93, 2010 | 162 | 2010 |
| Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis EM Bruscia, PX Zhang, A Satoh, C Caputo, R Medzhitov, A Shenoy, ... The Journal of Immunology 186 (12), 6990-6998, 2011 | 155 | 2011 |
| Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium NA McNeer, K Anandalingam, RJ Fields, C Caputo, S Kopic, A Gupta, ... Nature communications 6 (1), 6952, 2015 | 151 | 2015 |
| Effects of the Serine/Threonine Kinase SGK1 on the Epithelial Na+ Channel (ENaC) and CFTR: Implications for Cystic Fibrosis C Wagner, M Ott, K Klingel, S Beck, B Friedrich, KN Wild, S Bröer, ... Cellular Physiology and Biochemistry 11 (4), 209-218, 2001 | 147 | 2001 |
| Long-term treatment with oral N-acetylcysteine: affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial C Conrad, J Lymp, V Thompson, C Dunn, Z Davies, B Chatfield, D Nichols, ... Journal of Cystic Fibrosis 14 (2), 219-227, 2015 | 122 | 2015 |
| Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator EM Schwiebert, MM Morales, S Devidas, ME Egan, WB Guggino Proceedings of the National Academy of Sciences 95 (5), 2674-2679, 1998 | 109 | 1998 |
| Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation P Zhang, J Cheng, S Zou, AD D'Souza, JL Koff, J Lu, PJ Lee, DS Krause, ... Nature communications 6 (1), 6221, 2015 | 104 | 2015 |
| Surface modified poly (β amino ester)-containing nanoparticles for plasmid DNA delivery RJ Fields, CJ Cheng, E Quijano, C Weller, N Kristofik, N Duong, ... Journal of controlled release 164 (1), 41-48, 2012 | 103 | 2012 |
| Continuous detection of extracellular ATP on living cells by using atomic force microscopy SW Schneider, ME Egan, BP Jena, WB Guggino, H Oberleithner, ... Proceedings of the National Academy of Sciences 96 (21), 12180-12185, 1999 | 97 | 1999 |
| A functional CFTR-NBF1 is required for ROMK2-CFTR interaction CM McNicholas, MW Nason Jr, WB Guggino, EM Schwiebert, SC Hebert, ... American Journal of Physiology-Renal Physiology 273 (5), F843-F848, 1997 | 97 | 1997 |
