edward olejniczak
edward olejniczak
professor biochemistry vanderbilt university
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Cited by
Cited by
Structural biology of the Bcl-2 family of proteins
AM Petros, ET Olejniczak, SW Fesik
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1644 (2-3), 83-94, 2004
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
Z Liu, C Sun, ET Olejniczak, RP Meadows, SF Betz, T Oost, J Herrmann, ...
Nature 408 (6815), 1004-1008, 2000
Discovery of small molecules that bind to K‐Ras and inhibit Sos‐mediated activation
Q Sun, JP Burke, J Phan, MC Burns, ET Olejniczak, AG Waterson, T Lee, ...
Angewandte Chemie International Edition 51 (25), 6140-6143, 2012
Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies
AM Petros, DG Nettesheim, Y Wang, ET Olejniczak, RP Meadows, J Mack, ...
Protein Science 9 (12), 2528-2534, 2000
One-dimensional relaxation-and diffusion-edited NMR methods for screening compounds that bind to macromolecules
PJ Hajduk, ET Olejniczak, SW Fesik
Journal of the American Chemical Society 119 (50), 12257-12261, 1997
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
B Huang, M Eberstadt, ET Olejniczak, RP Meadows, SW Fesik
Nature 384 (6610), 638-641, 1996
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer
TK Oost, C Sun, RC Armstrong, AS Al-Assaad, SF Betz, TL Deckwerth, ...
Journal of medicinal chemistry 47 (18), 4417-4426, 2004
Discovery of potent nonpeptide inhibitors of stromelysin using SAR by NMR
PJ Hajduk, G Sheppard, DG Nettesheim, ET Olejniczak, SB Shuker, ...
Journal of the American Chemical Society 119 (25), 5818-5827, 1997
Structure and ligand recognition of the phosphotyrosine binding domain of Shc
MM Zhou, KS Ravichandran, ET Olejniczak, AM Petros, RP Meadows, ...
Nature 378 (6557), 584-592, 1995
Structural characterization of a soluble amyloid β-peptide oligomer
L Yu, R Edalji, JE Harlan, TF Holzman, AP Lopez, B Labkovsky, H Hillen, ...
Biochemistry 48 (9), 1870-1877, 2009
Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure …
G Liu, JR Huth, ET Olejniczak, R Mendoza, P DeVries, S Leitza, EB Reilly, ...
Journal of medicinal chemistry 44 (8), 1202-1210, 2001
Analysis of deuterium nuclear magnetic resonance line shapes in anisotropic media
RJ Wittebort, ET Olejniczak, RG Griffin
The Journal of chemical physics 86 (10), 5411-5420, 1987
A general method for assigning NMR spectra of denatured proteins using 3D HC (CO) NH-TOCSY triple resonance experiments
TM Logan, ET Olejniczak, RX Xu, SW Fesik
Journal of biomolecular NMR 3, 225-231, 1993
Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design
A Friberg, D Vigil, B Zhao, RN Daniels, JP Burke, PM Garcia-Barrantes, ...
Journal of medicinal chemistry 56 (1), 15-30, 2013
A novel MCL1 inhibitor combined with venetoclax rescues venetoclax-resistant acute myelogenous leukemia
HE Ramsey, MA Fischer, T Lee, AE Gorska, MP Arrate, L Fuller, KL Boyd, ...
Cancer discovery 8 (12), 1566-1581, 2018
Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein
Q Huang, L Yu, AM Petros, A Gunasekera, Z Liu, N Xu, P Hajduk, J Mack, ...
Biochemistry 43 (20), 6059-6063, 2004
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
LR Thomas, Q Wang, BC Grieb, J Phan, AM Foshage, Q Sun, ...
Molecular cell 58 (3), 440-452, 2015
Solution structure of a pleckstrin-homology domain
HS Yoon, PJ Hajduk, AM Petros, ET Olejniczak, RP Meadows, SW Fesik
Nature 369 (6482), 672-675, 1994
ALARM NMR: a rapid and robust experimental method to detect reactive false positives in biochemical screens
JR Huth, R Mendoza, ET Olejniczak, RW Johnson, DA Cothron, Y Liu, ...
Journal of the American Chemical Society 127 (1), 217-224, 2005
NMR studies of [U-13C] cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding
SW Fesik, RT Gampe Jr, HL Eaton, G Gemmecker, ET Olejniczak, P Neri, ...
Biochemistry 30 (26), 6574-6583, 1991
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